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- Table of Contents
Facts about Protein Wnt-9b.
Required for normal embryonic kidney growth, and also for normal development of the urogenital tract, such as uterus and a portion of the oviduct and the upper vagina in females, and epididymis and vas deferens in males. Activates a signaling cascade from the metanephric mesenchyme that induces tubulogenesis.
Human | |
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Gene Name: | WNT9B |
Uniprot: | O14905 |
Entrez: | 7484 |
Belongs to: |
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Wnt family |
Protein Wnt-14b; wingless-type MMTV integration site family, member 15; wingless-type MMTV integration site family, member 9B; Wnt-14b; WNT14Bprotein Wnt-9b; Wnt-15; WNT15Protein Wnt-15; Wnt9b; Wnt-9b
Mass (kDA):
39.001 kDA
Human | |
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Location: | 17q21.32 |
Sequence: | 17; NC_000017.11 (46833201..46886738) |
Moderately expressed in fetal kidney and adult kidney. Also found in brain.
Secreted, extracellular space, extracellular matrix. Secreted.
PMID: 11604992 by Kirikoshi H., et al. Molecular cloning and characterization of WNT14B, a novel member of the WNT gene family.
PMID: 9441749 by Bergstein I., et al. Isolation of two novel WNT genes, WNT14 and WNT15, one of which (WNT15) is closely linked to WNT3 on human chromosome 17q21.