Wbp2 Antibodies

AND Wbp2 ELISA kits, Wbp2 Proteins

Many biological assays use antibodies to detect Wbp2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Wbp2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Wbp2 antibodies...

We validate the specificity of these antibodies to Wbp2 by testing them on tissues known to express Wbp2 positively and negatively. Browse below to find the Wbp2 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Wbp2 Infographic by Boster Bio

All Wbp2 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Human WBP2 Recombinant Protein

SDS-PAGE

$250
Cat # PROTQ969T9
Starting from 10ug

Anti-WBP2 Antibody (C-term)

Human, Mouse

$299
Cat # M10191
50 µl

WBP2 (NM_012478) Human Over-expression Lysate

Human

$628
Cat # LS023558
100 µg

Wbp2 Overview

Facts about WW domain-binding protein 2.

WW domain-binding protein 2 (Wbp2)

Acts as transcriptional coactivator of estrogen and progesterone receptors (ESR1 and PGR) upon hormone stimulation. In presence of estrogen, binds to ESR1-responsive promoters.

Required for YAP1 coactivation function on PGR activity. Synergizes with WBP2 in improving PGR activity (By similarity).

Gene Information

Mouse
Gene Name:	Wbp2
Uniprot:	P97765
Entrez:	22378

Family

Belongs to:

No superfamily

Alternative Names

WBP-2MGC18269; WW domain binding protein 2; WW domain-binding protein 2

Molecular Weight

Mass (kDA):
28.032 kDA

Genomic Context


Mouse

Location:	11\|11 E2
Sequence:	11;

Tissue Specificity

Expressed in the ear and the eye (PubMed:26881968). Isoform 1 is expressed in brain, inner ear and organ of Corti. Isoform 2 is only detected in brain (PubMed:26881968).

Diseases

Neoplasms
Malignant Neoplasms
Malignant Neoplasm Of Breast
Dementia
Neoplasms, Experimental
Leukoencephalopathies
Edema
Vascular System Injuries
Animal Mammary Neoplasms
Cerebrovascular Accident
Mammary Neoplasms

Equine Leukoencephalomalacia
Cell Invasion
Cell Transformation, Neoplastic
Common Wart
Cognition Disorders
Tissue Adhesions

Pathways

Cell Growth
Cell Proliferation
Aging
Metaphase
Pathogenesis
Cell-cell Adhesion

PTMs

Phosphorylation

Ubiquitination

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Wbp2

References

PMID: 7644498 by Chen H.I., et al. The WW domain of Yes-associated protein binds a proline-rich ligand that differs from the consensus established for Src homology 3-binding modules.

PMID: 11042109 by Jolliffe C.N., et al. Identification of multiple proteins expressed in murine embryos as binding partners for the WW domains of the ubiquitin-protein ligase Nedd4.