Vacuolar protein-sorting-associated protein 25 (Vps25)

Part of the ESCRT-II complicated (endosomal sorting complex required for transport II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation.

The ESCRT-II complicated is probably involved in the recruiting of the ESCRT-III complicated. The ESCRT-II complex may also play a role in transcription regulation, possibly via its interaction with ELL (By similarity).