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- Table of Contents
Facts about Myeloid-derived growth factor.
Inhibits cardiac myocyte apoptosis in a PI3K/AKT-dependent signaling pathway. .
Mouse | |
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Gene Name: | Mydgf |
Uniprot: | Q9CPT4 |
Entrez: | 28106 |
Belongs to: |
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MYDGF family |
C19orf10; chromosome 19 open reading frame 10; EUROIMAGE1875335; IL25; IL27; IL27w; interleukin 27 working designation; Interleukin-25; Ly6elg; MYDGF; myeloid-derived growth factor; R33729_1; SF20; Stromal cell-derived growth factor SF20; UPF0556 protein C19orf10
Mass (kDA):
17.982 kDA
Mouse | |
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Location: | 17 D|17 29.2 cM |
Sequence: | 17; |
Expressed in prostate, spleen and lung, and weakly expressed in the left ventricle (LF) and liver. Expressed predominantly in inflammatory cells, such as monocytes and macrophages, and weakly expressed in neutrophils, T-cells, B- cells, endothelial cells and cardiac myocytes, after myocardial infarction (MI) (at protein level).
PMID: 11714798 by Tulin E.E., et al. SF20/IL-25, a novel bone marrow stroma-derived growth factor that binds to mouse thymic shared antigen-1 and supports lymphoid cell proliferation.
PMID: 15378209 by Wang P., et al. Profiling of the secreted proteins during 3T3-L1 adipocyte differentiation leads to the identification of novel adipokines.