VAMP2 Antibodies

AND VAMP2 ELISA kits, VAMP2 Proteins

Many biological assays use antibodies to detect VAMP2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with VAMP2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop VAMP2 antibodies...

We validate the specificity of these antibodies to VAMP2 by testing them on tissues known to express VAMP2 positively and negatively. Browse below to find the VAMP2 antibody that suites your experiment. We have 7 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Previous: CBLIF Next: XCL2

VAMP2 Infographic by Boster Bio

All VAMP2 Products

Product

Figures

Specificity

Applications

Price

Anti-VAMP2 Antibody

Bovine, Guinea pig, Human, Mouse, Rabbit, Rat

IP, ICC, WB

$594
Cat # A02331
200μg/vial

Anti-VAMP2 Rabbit Monoclonal Antibody

1 Q&As

Human, Mouse, Rat

Flow Cytometry, IP, IF, ICC, WB

$370
Cat # M02331-1
100 μl

Anti-VAMP2 Antibody

Human, Mouse, Rat

IHC, WB

$405
Cat # A02331-1
100ul

Anti-VAMP2 Antibody

Human, Mouse, Rat

Flow Cytometry, IP, IF, ICC, WB

$405
Cat # A02331-2
100ul

Human VAMP-2 Recombinant Protein

SDS-PAGE

$268
Cat # PROTP63027
Starting from 10ug

Mouse Vamp2 Recombinant Protein

SDS-PAGE

$275
Cat # PROTP63044
Starting from 10ug

VAMP2 (NM_014232) Human Over-expression Lysate

Human

$628
Cat # LS006844
100 µg

VAMP2 Overview

Facts about Vesicle-associated membrane protein 2.

VAMP2 3D structure. Source: alphafold

Vesicle-associated membrane protein 2 (VAMP2)

Involved in the targeting and/or fusion of transport vesicles to their target membrane. Modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1.

Gene Information

Human
Gene Name:	VAMP2
Uniprot:	P63027
Entrez:	6844

Family

Belongs to:

synaptobrevin family

Alternative Names

FLJ11460; SYB2; SYB2vesicle-associated membrane protein 2; synaptobrevin 2; synaptobrevin-2; VAMP2; VAMP-2; VAMP-2vesicle associated membrane protein 2; vesicle-associated membrane protein 2 (synaptobrevin 2)

Molecular Weight

Mass (kDA):
12.663 kDA

Genomic Context


Human

Location:	17p13.1
Sequence:	17; NC_000017.11 (8159147..8162948, complement)

Tissue Specificity

Nervous system and skeletal muscle.

Subcellular Localizations

Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Single-pass type IV membrane protein. Cell junction, synapse, synaptosome. Cell membrane. Neuronal synaptic vesicles. Colocalizes with PRKCZ and WDFY2 in intracellular vesicles (PubMed:17313651).

Diseases

Tetanus
Diabetes Mellitus
Nervousness
Insulin Resistance
Diabetes Mellitus, Non-insulin-dependent
Malignant Neoplasms
Impaired Cognition
Tissue Adhesions
Impairment (finding)
Neurodegenerative Disorders
Paralysis Flaccid
Nerve Degeneration

Alzheimer's Disease
Hyperglycemia
Pituitary Diseases
Pheochromocytoma
Colorectal Cancer
Cognition Disorders
Malignant Tumor Of Colon

Interacting Proteins

Picalm
PRKD3
SNAP29
SNCA
STX1A

STX4

Pathways

Exocytosis
Transport
Membrane Fusion
Secretion
Localization
Vesicle Fusion
Endocytosis
Glucose Transport
Insulin Secretion
Synaptic Vesicle Exocytosis
Synaptic Transmission
Vesicle Transport
Vesicle Docking

Synaptic Vesicle Fusion
Aging
Proteolysis
Snare Complex Assembly
Rna Interference
Cell Adhesion
Regeneration

PTMs

Cleavage
Phosphorylation
Prenylation
Biotinylation
Oxidation
Palmitoylation

Sulphation
Nitrosylation
Hydroxylation
Amidation
Dephosphorylation
Ubiquitination

Glycosylation

Research Areas

Membrane Vesicle Markers
Neuronal Cell Markers
Neuroscience
Neurotransmission

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/VAMP2

References

PMID: 1976629 by Archer B.T. III, et al. Structures and chromosomal localizations of two human genes encoding synaptobrevins 1 and 2.

PMID: 8760387 by Jagadish M.N., et al. Insulin-responsive tissues contain the core complex protein SNAP-25 (synaptosomal-associated protein 25) A and B isoforms in addition to syntaxin 4 and synaptobrevins 1 and 2.