Visual system homeobox 2 Antibodies

AND Vsx2 ELISA kits, Visual system homeobox 2 Proteins

Many biological assays use antibodies to detect Visual system homeobox 2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Visual system homeobox 2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Visual system homeobox 2 antibodies...

We validate the specificity of these antibodies to Visual system homeobox 2 by testing them on tissues known to express Vsx2 positively and negatively. Browse below to find the Vsx2 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Vsx2 Infographic by Boster Bio

All Vsx2 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-CHX10/VSX2 Antibody Picoband®

3 Q&As

Human, Mouse

$370
Cat # A05180
100 μg/vial

CHX10 (VSX2) (NM_182894) Human Recombinant Protein

$1062
Cat # PROTP58304
20 µg

Anti-CHX10 Rabbit Monoclonal Antibody

Human, Mouse, Rat

Flow Cytometry, WB

$370
Cat # M05180
100 μl/vial

CHX10 (VSX2) (NM_182894) Human Over-expression Lysate

Human

$628
Cat # LS338917
100 µg

Vsx2 Overview

Facts about Visual system homeobox 2.

Visual system homeobox 2 (Vsx2)

Plays a significant role in the specification and morphogenesis of the sensory retina. May also take part in the growth of the cells of the inner nuclear layer, especially bipolar cells.

Gene Information

Mouse
Gene Name:	Vsx2
Uniprot:	Q61412
Entrez:	12677

Family

Belongs to:

paired homeobox family

Alternative Names

ceh-10 homeo domain containing homolog (C. elegans); ceh-10 homeo domain containing homolog; ceh-10 homeodomain containing homolog (C. elegans); Ceh-10 homeodomain-containing homolog; CHX10MCOPCB3; Homeobox protein CHX10; HOX10C elegans ceh-10 homeo domain-containing homolog; MCOP2; RET1; visual system homeobox 2

Molecular Weight

Mass (kDA):
39.436 kDA

Genomic Context


Mouse

Location:	12 D1\|12 39.28 cM
Sequence:	12;

Tissue Specificity

Expressed throughout the anterior optic vesicle and all neuroblasts of the optic cup. In the mature retina Is restricted to the inner nuclear layer, in which its expression decreases from the outer to the inner margin. Also detected in regions of the developing thalamus, hindbrain, and ventral spinal cord.

Diseases

Microphthalmos
Anophthalmos
Eye Abnormalities
Blind Vision
Nervousness
Congenital Ocular Coloboma (disorder)
Retinal Degeneration
Protrusion
Blindness Congenital
Chromosomal Translocation
Retinoblastoma
Leukemia

Retinal Dystrophies
Adenoma
Non-neoplastic Disorder
Spinal Cord Injuries
Radiation Injuries, Experimental
Malignant Neoplasms

Pathways

Cell Proliferation
Eye Development
Cell Cycle
Locomotion
Neurogenesis
Cell Differentiation
Localization
Pigmentation
Cell Fate Determination
Cell Fate Specification
Cell Division
Swimming
Epithelium Development

Transdifferentiation
Regeneration
Transport
Cell Migration
Dna Hypermethylation
Photoreceptor Cell Fate Determination
Cell Maturation

PTMs

Methylation

Research Areas

Vision

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Vsx2

References

PMID: 7914735 by Liu I.S.C., et al. Developmental expression of a novel murine homeobox gene (Chx10): evidence for roles in determination of the neuroretina and inner nuclear layer.

PMID: 8630490 by Burmeister M., et al. Ocular retardation mouse caused by Chx10 homeobox null allele: impaired retinal progenitor proliferation and bipolar cell differentiation.