CIDEA Antibodies

AND CIDEA ELISA kits, CIDEA Proteins

Many biological assays use antibodies to detect CIDEA, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CIDEA in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CIDEA antibodies...

We validate the specificity of these antibodies to CIDEA by testing them on tissues known to express CIDEA positively and negatively. Browse below to find the CIDEA antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CIDEA Infographic by Boster Bio

All CIDEA Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-CIDE-A Antibody

Human

ELISA, IF, IHC-P, WB

$449
Cat # A02671
0.1 mg

Anti-CIDE-A Antibody

Human, Mouse

ELISA, IF, IHC-P, WB

$449
Cat # A02671-1
0.1 mg

CIDE A (CIDEA) (NM_198289) Human Over-expression Lysate

Human

$628
Cat # LS001149
100 µg

CIDEA Overview

Facts about Cell death activator CIDE-A.

CIDEA 3D structure. Source: alphafold

Cell death activator CIDE-A (CIDEA)

Acts as a CEBPB coactivator in mammary epithelial cells to control the expression of a subset of CEBPB downstream target genes, such as ID2, IGF1, PRLR, SOCS1, SOCS3, XDH, but not casein. By interacting with CEBPB, strengthens the institution of CEBPB using the XDH promoter, increases histone acetylation and dissociates HDAC1 in the promoter (By similarity).

Binds to lipid droplets and modulates their enlargement, thereby restricting lipolysis and favoring storage. At focal contact sites between lipid droplets, promotes directional internet neutral lipid transfer from the smaller to larger lipid droplets.

Gene Information

Human
Gene Name:	CIDEA
Uniprot:	O60543
Entrez:	1149

Family

Belongs to:

No superfamily

Alternative Names

cell death activator CIDE-A; cell death-inducing DFFA-like effector aCIDE-A; CIDEA

Molecular Weight

Mass (kDA):
24.687 kDA

Genomic Context


Human

Location:	18p11.21\|18
Sequence:	18; NC_000018.10 (12254361..12277595)

Tissue Specificity

Expressed in omental and subcutaneous adipose tissue (at protein level).

Subcellular Localizations

Lipid droplet. Nucleus. Enriched at lipid droplet contact sites. Has been shown to localize to mitochondria, where it could interact with UCP1 and hence inhibit UCP1 uncoupling activity (By similarity). These data could not be confirmed (PubMed:18509062).

Diseases

Obesity
Steatohepatitis
Steatosis
Diabetes Mellitus
Inflammation
Insulin Resistance
Fatty Liver
Insulin Sensitivity
Metabolic Syndrome X
Metabolic Diseases
Neoplasms
Diabetes Mellitus, Non-insulin-dependent

Dyslipidemias
Adenoma
Carcinoma
Malignant Neoplasms
Impaired Glucose Tolerance
Hyperinsulinism
Inflammatory Response

Pathways

Energy Homeostasis
Cell Death
Fatty Acid Oxidation
Secretion
Transport
Immune Response
Inflammatory Response
Lipid Homeostasis
Lipid Storage
Glycosylation
Methylation
Lipid Oxidation
Rna Interference

Glycolysis
Cell Adhesion
Gene Silencing
Tricarboxylic Acid Cycle
Programmed Cell Death
Gluconeogenesis
Muscle Contraction

PTMs

Oxidation
Phosphorylation
Methylation
Ubiquitination

Demethylation
Cleavage
Glycosylation
Deglycosylation

Research Areas

Apoptosis

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CIDEA

References

PMID: 9564035 by Inohara N., et al. CIDE, a novel family of cell death activators with homology to the 45 kDa subunit of the DNA fragmentation factor.

PMID: 18509062 by Puri V., et al. Cidea is associated with lipid droplets and insulin sensitivity in humans.