Vam6/Vps39-like protein Antibodies

AND VPS39 ELISA kits, Vam6/Vps39-like protein Proteins

Many biological assays use antibodies to detect Vam6/Vps39-like protein, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Vam6/Vps39-like protein in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Vam6/Vps39-like protein antibodies...

We validate the specificity of these antibodies to Vam6/Vps39-like protein by testing them on tissues known to express VPS39 positively and negatively. Browse below to find the VPS39 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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VPS39 Infographic by Boster Bio

All VPS39 Products

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Product

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Specificity

Applications

Price

Anti-Vam6/Vps39-like protein VPS39 Antibody

Human, Mouse, Rat

ELISA, IF, IHC-P, WB

$449
Cat # A05711
0.1 mg

VPS39 (NM_015289) Human Recombinant Protein

$1062
Cat # PROTQ96JC1
20 µg

VPS39 (NM_015289) Human Over-expression Lysate

Human

$628
Cat # LS023339
100 µg

VPS39 Overview

Facts about Vam6/Vps39-like protein.

VPS39 3D structure. Source: alphafold

Vam6/Vps39-like protein (VPS39)

Regulator of TGF-beta/activin signaling, inhibiting SMAD3- and sparking SMAD2-dependent transcription. Acts by interfering with SMAD3/SMAD4 complex formation, this would lead to inhibition of SMAD3-dependent transcription and relieve SMAD3 inhibition of SMAD2-dependent promoters, thus increasing SMAD2- dependent transcription.

Does not affect TGF-beta-induced SMAD2 or SMAD3 phosphorylation, nor SMAD2/SMAD4 complex formation. .

Gene Information

Human
Gene Name:	VPS39
Uniprot:	Q96JC1
Entrez:	23339

Family

Belongs to:

VAM6/VPS39 family

Alternative Names

hVam6p; KIAA0770FLJ21681; TLP; TRAP1-like protein; vacuolar protein sorting 39 (yeast); vacuolar protein sorting 39 homolog (S. cerevisiae); vam6/Vps39-like protein; VAM6FLJ46546

Molecular Weight

Mass (kDA):
101.809 kDA

Genomic Context


Human

Location:	15q15.1
Sequence:	15; NC_000015.10 (42158701..42208331, complement)

Tissue Specificity

Widely expressed, with highest levels in heart, skeletal muscle, kidney, pancreas, brain, placenta and spleen.

Subcellular Localizations

Cytoplasm. Lysosome membrane; Peripheral membrane protein. Late endosome membrane; Peripheral membrane protein. Late endosome. Lysosome. Colocalizes with TGFBR1 and TGFBR2 in cytoplasmic vesicular structures and most prominently in cortical vesicles.