Vax2 Antibodies

AND Vax2 ELISA kits, Vax2 Proteins

Many biological assays use antibodies to detect Vax2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Vax2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Vax2 antibodies...

We validate the specificity of these antibodies to Vax2 by testing them on tissues known to express Vax2 positively and negatively. Browse below to find the Vax2 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Vax2 Infographic by Boster Bio

All Vax2 Products

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Product

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Specificity

Applications

Price

Anti-Ventral anterior homeobox 2 VAX2 Antibody

Human, Mouse, Rat

ELISA, WB

$380
Cat # A10557
100ul

VAX2 (NM_012476) Human Over-expression Lysate

Human

$628
Cat # LS025806
100 µg

Vax2 Overview

Facts about Ventral anterior homeobox 2.

Ventral anterior homeobox 2 (Vax2)

Transcription factor that may be the dorsoventral specification of the forebrain. Regulates the expression of Wnt signaling antagonists such as the expression of a truncated TCF7L2 isoform that can't bind CTNNB1 and acts so as a potent dominant-negative Wnt antagonist.

Plays a crucial role in eye development and, in particular, in the specification of the ventral optic vesicle. May be a regulator of axial polarization in the retina.

Gene Information

Mouse
Gene Name:	Vax2
Uniprot:	Q9WTP9
Entrez:	24113

Family

Belongs to:

EMX homeobox family

Alternative Names

DRES93; ventral anterior homeobox 2

Molecular Weight

Mass (kDA):
31.701 kDA

Genomic Context


Mouse

Location:	6 C3\|6 35.94 cM
Sequence:	6;

Tissue Specificity

Expressed in the developing and mature retina.

Diseases

Congenital Ocular Coloboma (disorder)
Microphthalmos
Eye Abnormalities
Nervousness
Cleft Lip
Congenital Abnormality
Cleft Palate
Vitamin A Deficiency
Retinal Degeneration
Muscular Fasciculation
Fetal Alcohol Syndrome
Fundus Coloboma

Pathologic Neovascularization
Dysequilibrium Syndrome
Cell Invasion
Congenital Absence
Chromosomal Duplication
Corneal Neovascularization

Pathways

Eye Development
Cell Differentiation
Cell Proliferation
Localization
Neural Tube Closure
Tissue Morphogenesis
Neurogenesis
Eye Morphogenesis
Tube Closure
Organ Development
Cell Cycle

Cell Death
Axon Guidance
Paracrine Signaling
Forebrain Development
Sensory Perception
Necroptosis

PTMs

Phosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Vax2

References

PMID: 10421837 by Ohsaki K., et al. Expression of the Vax family homeobox genes suggests multiple roles in eye development.

PMID: 10485894 by Barbieri A.M., et al. A homeobox gene, vax2, controls the patterning of the eye dorsoventral axis.