VAT1 Antibodies

AND VAT1 ELISA kits, VAT1 Proteins

Many biological assays use antibodies to detect VAT1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with VAT1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop VAT1 antibodies...

We validate the specificity of these antibodies to VAT1 by testing them on tissues known to express VAT1 positively and negatively. Browse below to find the VAT1 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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VAT1 Infographic by Boster Bio

All VAT1 Products

Product

Figures

Specificity

Applications

Price

Anti-VAT1 Antibody

Human, Mouse, Rat

ELISA, WB

$380
Cat # A08521
100ul

VAT1 (NM_006373) Human Recombinant Protein

$1249
Cat # PROTQ99536
20 µg

VAT1 (NM_006373) Human Over-expression Lysate

Human

$628
Cat # LS010493
100 µg

VAT1 Overview

Facts about Synaptic vesicle membrane protein VAT-1 homolog.

VAT1 3D structure. Source: alphafold

Synaptic vesicle membrane protein VAT-1 homolog (VAT1)

Possesses ATPase activity (By similarity). Plays a part in calcium-regulated keratinocyte activation in epidermal repair mechanisms.

Has no effect on cell proliferation. Negatively regulates mitochondrial fusion in cooperation with mitofusin proteins (MFN1-2).

Gene Information

Human
Gene Name:	VAT1
Uniprot:	Q99536
Entrez:	10493

Family

Belongs to:

zinc-containing alcohol dehydrogenase family

Alternative Names

FLJ20230; membrane protein of cholinergic synaptic vesicles; synaptic vesicle membrane protein VAT-1 homolog; VATI; vesicle amine transport protein 1 homolog (T. californica)

Molecular Weight

Mass (kDA):
41.92 kDA

Genomic Context


Human

Location:	17q21.31
Sequence:	17; NC_000017.11 (43014607..43022385, complement)

Tissue Specificity

Expressed in brain. Also expressed in glioblastoma cells.

Subcellular Localizations

Cytoplasm. Mitochondrion outer membrane; Peripheral membrane protein. The majority is localized in the cytoplasm and a small amount is associated with mitochondria.

Diseases

Malignant Neoplasms
Mammary Neoplasms
Chromosomal Deletion
Malignant Neoplasm Of Breast
Hypoxia
Neoplasms
Hereditary Breast And Ovarian Cancer Syndrome
Malignant Neoplasm Of Ovary
Endocrine System Diseases

Cytogenetic Abnormality
Bilateral Breast Cancer
Ovarian Neoplasm

Pathways

Transport
Amine Transport
Localization
Cell Cycle
Protein Targeting
Muscle Contraction

PTMs

Acetylation

Phosphoprotein

Research Areas

Protein Kinase

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/VAT1

References

PMID: 8938427 by Smith T.M., et al. Complete genomic sequence and analysis of 117 kb of human DNA containing the gene BRCA1.

PMID: 7774926 by Friedman L.S., et al. 22 genes from chromosome 17q21: cloning, sequencing, and characterization of mutations in breast cancer families and tumors.