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- Table of Contents
Facts about Vang-like protein 2.
Required for polarization and movement of myocardializing cells in the outflow tract and seems to act via RHOA signaling to regulate this procedure. Required for cell surface localization of FZD3 and FZD6 in the inner ear (By similarity).
Human | |
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Gene Name: | VANGL2 |
Uniprot: | Q9ULK5 |
Entrez: | 57216 |
Belongs to: |
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Vang family |
KIAA1215Loop-tail protein 1 homolog; loop-tail-associated protein; LPP1; LTAP; LTAPVan Gogh-like protein 2; MGC119403; MGC119404; STB1; STB1Strabismus 1; STBM; STBM1; Strabismus; vang (van gogh, Drosophila)-like 2, vang, van gogh-like 2 (Drosophila); Vang like Protein 2; VANGL2; vang-like 2 (van gogh, Drosophila); Vang-like Protein 2
Mass (kDA):
59.714 kDA
Human | |
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Location: | 1q23.2 |
Sequence: | 1; NC_000001.11 (160400564..160428674) |
Cell membrane; Multi-pass membrane protein.
PMID: 20558380 by Lei Y.P., et al. VANGL2 mutations in human cranial neural-tube defects.