USP2 Antibodies

AND USP2 ELISA kits, USP2 Proteins

Many biological assays use antibodies to detect USP2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with USP2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop USP2 antibodies...

We validate the specificity of these antibodies to USP2 by testing them on tissues known to express USP2 positively and negatively. Browse below to find the USP2 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Previous: CCN4 Next: USP10

USP2 Infographic by Boster Bio

All USP2 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

USP2 (NM_171997) Human Recombinant Protein

$813
Cat # PROTO75604
20 µg

Anti-USP2 Antibody

African green monkey, Human

$299
Cat # M04288
50 µl

USP2 (NM_004205) Human Over-expression Lysate

Human

$628
Cat # LS009099
100 µg

USP2 Overview

Facts about Ubiquitin carboxyl-terminal hydrolase 2.

USP2 3D structure. Source: alphafold

Ubiquitin carboxyl-terminal hydrolase 2 (USP2)

Hydrolase which deubiquitinates polyubiquitinated target proteins such as MDM2, MDM4 and CCND1 (PubMed:17290220, PubMed:19917254, PubMed:19838211). Isoform 1 and isoform 4 possess both ubiquitin-specific peptidase and isopeptidase activities (By similarity).

Deubiquitinates MDM2 without reversing MDM2-mediated p53/TP53 ubiquitination and consequently indirectly promotes p53/TP53 degradation and limits p53 activity (PubMed:17290220, PubMed:19838211). Has no deubiquitinase activity against p53/TP53 (PubMed:17290220).

Gene Information

Human
Gene Name:	USP2
Uniprot:	O75604
Entrez:	9099

Family

Belongs to:

peptidase C19 family

Alternative Names

Deubiquitinating enzyme 2; EC 3.1.2.15; EC 3.4.19.12,41 kDa ubiquitin-specific protease; ubiquitin specific peptidase 2; ubiquitin specific protease 12; ubiquitin specific protease 2; ubiquitin specific protease 9; ubiquitin thioesterase 2; Ubiquitin thiolesterase 2; Ubiquitin-specific-processing protease 2; UBP41; UBP41ubiquitin carboxyl-terminal hydrolase 2; USP2; USP9

Molecular Weight

Mass (kDA):
68.072 kDA

Genomic Context


Human

Location:	11q23.3
Sequence:	11; NC_000011.10 (119355215..119381690, complement)

Tissue Specificity

Expressed in mesangial cells of the kidney and in different types of glomerulonephritides (at protein level).

Subcellular Localizations

Cytoplasm. Cytoplasm, perinuclear region. Localizes in the spermatid head in late-elongating spermatids in the thin area between the outer acrosomal membrane and the plasma membrane.; [Isoform 4]: Nucleus. Membrane; Peripheral membrane protein. Cytoplasm. Predominantly expressed at membranes.