UQCRC2 Antibodies

AND UQCRC2 ELISA kits, UQCRC2 Proteins

Many biological assays use antibodies to detect UQCRC2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with UQCRC2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop UQCRC2 antibodies...

We validate the specificity of these antibodies to UQCRC2 by testing them on tissues known to express UQCRC2 positively and negatively. Browse below to find the UQCRC2 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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UQCRC2 Infographic by Boster Bio

All UQCRC2 Products

Product

Figures

Specificity

Applications

Price

Anti-UQCRC2 Monoclonal Antibody

1 Q&As

Human, Mouse, Rat

Flow Cytometry, IP, IF, IHC, ICC, WB

$370
Cat # M07937
100 μl

Human UQCRC2 Recombinant Protein

SDS-PAGE, Denatured

$265
Cat # PROTP22695
Starting from 10ug

UQCRC2 (NM_003366) Human Over-expression Lysate

Human

$628
Cat # LS007385
100 µg

UQCRC2 Overview

Facts about Cytochrome b-c1 complex subunit 2, mitochondrial.

UQCRC2 3D structure. Source: alphafold

Cytochrome b-c1 complex subunit 2, mitochondrial (UQCRC2)

This is a component of this ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. The core protein 2 is required for the assembly of the complex.

Gene Information

Human
Gene Name:	UQCRC2
Uniprot:	P22695
Entrez:	7385

Family

Belongs to:

peptidase M16 family

Alternative Names

Complex III subunit 2; Core protein II; cytochrome b-c1 complex subunit 2, mitochondrial; QCR2; ubiquinol-cytochrome c reductase core protein II; Ubiquinol-cytochrome-c reductase complex core protein 2; UQCR2

Molecular Weight

Mass (kDA):
48.443 kDA

Genomic Context


Human

Location:	16p12.2
Sequence:	16; NC_000016.10 (21953361..21983660)

Subcellular Localizations

Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.

Diseases

Infertility
Juvenile Neuronal Ceroid Lipfuscinosis
Spinal Cord Injuries
Male Infertility
Nerve Degeneration
Respiratory Hypersensitivity
Malignant Neoplasm Of Breast
Cardiomyopathy, Familial Idiopathic
Subfertility
Neuronal Ceroid-lipofuscinoses
Human Mammary Carcinoma
Carcinoma
Malignant Neoplasms

Nervousness
Asthma
Ductal Carcinoma
Attention Deficit Hyperactivity Disorder
Allergy
Inflammation
Mammary Neoplasms

Interacting Proteins

CACNA1A

Pathways

Localization
Regeneration
Lipid Homeostasis
Fertilization
Oxidative Phosphorylation

PTMs

Phosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/UQCRC2

References

PMID: 2547763 by Hosokawa Y., et al. Complementary DNA encoding core protein II of human mitochondrial cytochrome bc1 complex. Substantial diversity in deduced primary structure from its yeast counterpart.

PMID: 23281071 by Miyake N., et al. Mitochondrial complex III deficiency caused by a homozygous UQCRC2 mutation presenting with neonatal-onset recurrent metabolic decompensation.