Uridine phosphorylase 1 Antibodies

AND UPP1 ELISA kits, Uridine phosphorylase 1 Proteins

Many biological assays use antibodies to detect Uridine phosphorylase 1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Uridine phosphorylase 1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Uridine phosphorylase 1 antibodies...

We validate the specificity of these antibodies to Uridine phosphorylase 1 by testing them on tissues known to express UPP1 positively and negatively. Browse below to find the UPP1 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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UPP1 Infographic by Boster Bio

All UPP1 Products

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Product

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Specificity

Applications

Price

Anti-Uridine phosphorylase 1 UPP1 Antibody

Human

$405
Cat # A10128
100ul

Human UPP1 Recombinant Protein

SDS-PAGE

$265
Cat # PROTQ16831
Starting from 10ug

Anti-UPP1 Rabbit Monoclonal Antibody

Human, Mouse, Rat

$370
Cat # M10128
100 μl/vial

Uridine Phosphorylase 1 (UPP1) (NM_003364) Human Over-expression Lysate

Human

$628
Cat # LS007378
100 µg

UPP1 Overview

Facts about Uridine phosphorylase 1.

UPP1 3D structure. Source: alphafold

Uridine phosphorylase 1 (UPP1)

Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine into uracil and ribose- or deoxyribose-1- phosphate (PubMed:7488099). The produced molecules are subsequently utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.

Gene Information

Human
Gene Name:	UPP1
Uniprot:	Q16831
Entrez:	7378

Family

Belongs to:

PNP/UDP phosphorylase family

Alternative Names

EC 2.4.2.3; UDPRASE; UDRPASE; UP; UPASE 1; UPASE; UPP; UPP1; UPUPase 1; UrdPase 1; uridine phosphorylase 1; uridine phosphorylase

Molecular Weight

Mass (kDA):
33.934 kDA

Genomic Context


Human

Location:	7p12.3
Sequence:	7; NC_000007.14 (48088308..48108736)

Diseases

Malignant Neoplasms
Cell Transformation, Neoplastic
Mitochondrial Encephalomyopathies
Graft-vs-host Disease
Microsatellite Instability
Osteosarcoma
Autistic Disorder
Neoplasms
Pancreatic Neoplasm

Malignant Neoplasm Of Pancreas
Alzheimer's Disease
Autism Spectrum Disorders
Mitochondrial Neurogastrointestinal Encephalopathy Syndrome

Pathways

Mitochondrial Dna Replication
Dna Replication
Cell Cycle
Fertilization
Oocyte Maturation
Excretion
Hormone Secretion

Secretion

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/UPP1

References

PMID: 7488099 by Watanabe S., et al. Cloning and expression of human uridine phosphorylase.

PMID: 19291308 by Roosild T.P., et al. Implications of the structure of human uridine phosphorylase 1 on the development of novel inhibitors for improving the therapeutic window of fluoropyrimidine chemotherapy.