Protein unc-45 homolog A Antibodies

AND UNC45A ELISA kits, Protein unc-45 homolog A Proteins

Many biological assays use antibodies to detect Protein unc-45 homolog A, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Protein unc-45 homolog A in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Protein unc-45 homolog A antibodies...

We validate the specificity of these antibodies to Protein unc-45 homolog A by testing them on tissues known to express UNC45A positively and negatively. Browse below to find the UNC45A antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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UNC45A Infographic by Boster Bio

All UNC45A Products

Product

Figures

Specificity

Applications

Price

Anti-UNC45A Antibody (Monoclonal, AbS1)

5 Q&As

Human, Mouse, Rat

$297
Cat # M08608
50μg/vial

UNC45A (NM_001039675) Human Recombinant Protein

$1249
Cat # PROTQ9H3U1
20 µg

UNC45A (NM_001039675) Human Over-expression Lysate

Human

$628
Cat # LS055898
100 µg

UNC45A Overview

Facts about Protein unc-45 homolog A.

UNC45A 3D structure. Source: alphafold

Protein unc-45 homolog A (UNC45A)

Acts as co-chaperone for HSP90.
Prevents the stimulation of HSP90AB1 ATPase activity by AHSA1.

Positive factor in promoting PGR function in the cell. May be necessary for proper folding of myosin (Potential).

Gene Information

Human
Gene Name:	UNC45A
Uniprot:	Q9H3U1
Entrez:	55898

Family

Belongs to:

No superfamily

Alternative Names

FLJ10043; GCUNC45; GC-UNC45; GCUNC-45; general cell UNC45; protein unc-45 homolog A; SMAP-1IRO039700; SMAP1UNC-45A; smooth muscle cell associated protein-1; Smooth muscle cell-associated protein 1; unc-45 homolog A (C. elegans); Unc-45A

Molecular Weight

Mass (kDA):
103.077 kDA

Genomic Context


Human

Location:	15q26.1
Sequence:	15; NC_000015.10 (90930180..90954093)

Subcellular Localizations

Cytoplasm. Cytoplasm, perinuclear region. Nucleus. Predominant in the perinuclear region. Little protein in the nucleus.

Diseases

Neoplasm Metastasis
Carcinoma
Malignant Neoplasms
Cell Invasion
Neuroblastoma
Malignant Neoplasm Of Breast
Bone Neoplasms
Arteriovenous Malformation
Cystadenoma
Congenital Disorders
Osteosarcoma
Tumor Angiogenesis

Neoplasms
Cystadenocarcinoma, Serous
Mammary Neoplasms
Malignant Neoplasm Of Ovary
Chimera Disorder
Epithelial Ovarian Cancer
Ovarian Neoplasm

Interacting Proteins

MAX
MEOX2

Pathways

Cell Proliferation
Cell Division
Interphase
Angiogenesis
Myoblast Differentiation
Cytokinesis

PTMs

Cleavage

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/UNC45A

References

PMID: 12119110 by Marcos I., et al. Cloning, characterization and chromosome mapping of the human SMAP1 gene.

PMID: 16478993 by Chadli A., et al. GCUNC-45 is a novel regulator for the progesterone receptor/hsp90 chaperoning pathway.