UGT8 Antibodies

AND UGT8 ELISA kits, UGT8 Proteins

Many biological assays use antibodies to detect UGT8, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with UGT8 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop UGT8 antibodies...

We validate the specificity of these antibodies to UGT8 by testing them on tissues known to express UGT8 positively and negatively. Browse below to find the UGT8 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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UGT8 Infographic by Boster Bio

All UGT8 Products

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Product

Figures

Specificity

Applications

Price

Anti-UGT8 Antibody

Human, Mouse, Rat

$405
Cat # A07967
100ul

Anti-UGT8 Antibody

Human, Rat

IHC, WB

$380
Cat # A07967-1
100ul

Human uGT8 Recombinant Protein

SDS-PAGE, Denatured

$250
Cat # PROTQ16880
Starting from 20ug

UGT8 Overview

Facts about 2-hydroxyacylsphingosine 1-beta-galactosyltransferase.

UGT8 3D structure. Source: alphafold

2-hydroxyacylsphingosine 1-beta-galactosyltransferase (UGT8)

Catalyzes the transfer of galactose to ceramide, a key enzymatic step in the biosynthesis of galactocerebrosides, which are abundant sphingolipids of the myelin membrane of the central nervous system and peripheral nervous system. .

Gene Information

Human
Gene Name:	UGT8
Uniprot:	Q16880
Entrez:	7368

Family

Belongs to:

UDP-glycosyltransferase family

Alternative Names

Ceramide UDP-galactosyltransferase; Cerebroside synthase; CGT2-hydroxyacylsphingosine 1-beta-galactosyltransferase; EC 2.4.1; EC 2.4.1.45; UDP glycosyltransferase 8; UDP-galactose ceramide galactosyltransferase; UDP-galactose-ceramide galactosyltransferase; UGT4; uridine diphosphate glycosyltransferase 8

Molecular Weight

Mass (kDA):
61.438 kDA

Genomic Context


Human

Location:	4q26
Sequence:	4; NC_000004.12 (114598402..114687914)

Subcellular Localizations

Membrane; Single-pass membrane protein.

Diseases

Malignant Neoplasms
Neoplasms
Malignant Neoplasm Of Breast
Mammary Neoplasms
Neoplasm Metastasis
Metastatic Malignant Neoplasm To The Lung
Nervousness
Bipolar Disorder
Neuroblastoma
Lung Neoplasms
Schizophrenia
Oligodendroglioma
Tissue Adhesions

Leukodystrophy
Ductal Breast Carcinoma
Disease Of Adrenal Medulla
Nodular Glomerulosclerosis
Mood Disorders
Diabetic Nephropathy
Macule

Pathways

Myelination
Brain Development
Localization
Cell Adhesion
Transport
Glycosylation
Conjugation
Reflex
Schwann Cell Differentiation
Cell Death

Cell Cycle
Cell Differentiation
Cell Communication
Pathogenesis
Oligodendrocyte Differentiation

PTMs

Glycoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/UGT8

References

PMID: 8661025 by Bosio A., et al. The human gene CGT encoding the UDP-galactose ceramide galactosyl transferase (cerebroside synthase): cloning, characterization, and assignment to human chromosome 4, band q26.

PMID: 9125199 by Kapitonov D.E., et al. Cloning, characterization, and expression of human ceramide galactosyltransferase cDNA.