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- Table of Contents
1 Q&As
Facts about Urocortin.
Plays a role in the establishment of normal hearing thresholds (By similarity). Reduces food intake and modulates ghrelin levels in gastric body and plasma (By similarity).
Human | |
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Gene Name: | UCN |
Uniprot: | P55089 |
Entrez: | 7349 |
Belongs to: |
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sauvagine/corticotropin-releasing factor/urotensin I family |
MGC129974; MGC129975; UCN; UI; UROC; Urocortin; urocortin, preproprotein; UROCUI
Mass (kDA):
13.458 kDA
Human | |
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Location: | 2p23.3 |
Sequence: | 2; NC_000002.12 (27307400..27308445, complement) |
Keratinocytes in epidermis and the outer and inner root sheaths of hair follicles, epithelium of sebaceous and sweat glands, erector pili muscle, cutaneous blood vessel walls, cutaneous nerves and dermal mononuclear cells (PubMed:10690896). Detected in plasma cells in the lamia propria in colon mucosa (PubMed:15531481) (at protein level). Expressed in pituitary and adrenal glands (PubMed:10690896). Detected in plasma cells in the lamia propria in colon mucosa (PubMed:15531481).
Secreted.
PMID: 8612563 by Donaldson C.J., et al. Cloning and characterization of human urocortin.
PMID: 9628819 by Zhao L., et al. The structures of the mouse and human urocortin genes (Ucn and UCN).