UBE2N Antibodies

AND UBE2N ELISA kits, UBE2N Proteins

Many biological assays use antibodies to detect UBE2N, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with UBE2N in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop UBE2N antibodies...

We validate the specificity of these antibodies to UBE2N by testing them on tissues known to express UBE2N positively and negatively. Browse below to find the UBE2N antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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UBE2N Infographic by Boster Bio

All UBE2N Products

Product

Figures

Specificity

Applications

Price

Anti-UBC13 UBE2N Antibody

Human, Mouse, Rat

ELISA, IF, IHC-P, WB

$449
Cat # A02462-1
0.1 mg

UBE2N (NM_003348) Human Recombinant Protein

$1249
Cat # PROTP61088
20 µg

Anti-Ube2N / Ubc13 Rabbit Monoclonal Antibody

Human, Mouse, Rat

IF, IHC, ICC, WB

$370
Cat # M02462-1
100 μl/vial

Anti-Ubc13/UBE2N Antibody Picoband™

Human, Mouse, Rat

ELISA, Flow Cytometry, IF, ICC, WB

$370
Cat # A02462-2
100 μg/vial

UBE2N (NM_003348) Human Over-expression Lysate

Human

$628
Cat # LS007334
100 µg

UBE2N Overview

Facts about Ubiquitin-conjugating enzyme E2 N.

UBE2N 3D structure. Source: alphafold

Ubiquitin-conjugating enzyme E2 N (UBE2N)

This type of polyubiquitination does not lead to protein degradation by the proteasome. Mediates transcriptional activation of target genes.

Plays a role in the control of progress through the cell cycle and differentiation. Plays a role in the error-free DNA repair pathway also contributes to the survival of cells after DNA damage.

Gene Information

Human
Gene Name:	UBE2N
Uniprot:	P61088
Entrez:	7334

Family

Belongs to:

ubiquitin-conjugating enzyme family

Alternative Names

bendless-like ubiquitin conjugating enzyme; Bendless-like ubiquitin-conjugating enzyme; BLU; EC 6.3.2.19; MGC131857; MGC8489; UBC13; UbcH13; UbcH-ben; UBE2N; Ubiquitin carrier protein N; ubiquitin-conjugating enzyme E2 N; ubiquitin-conjugating enzyme E2N (homologous to yeast UBC13); ubiquitin-conjugating enzyme E2N (UBC13 homolog, yeast); Ubiquitin-protein ligase N; yeast UBC13 homolog

Molecular Weight

Mass (kDA):
17.138 kDA

Genomic Context


Human

Location:	12q22
Sequence:	12; NC_000012.12 (93405684..93442336, complement)

Subcellular Localizations

Nucleus. Cytoplasm.

Diseases

Malignant Neoplasms
Neoplasms
Malignant Neoplasm Of Breast
Ataxia
Genomic Instability
Ataxia Telangiectasia
Carcinoma
Immunologic Deficiency Syndromes
Lymphoma
Genotoxic Stress
Lymphoma, Non-hodgkin
Malignant Neoplasm Of Lung
Lung Neoplasms

Telangiectasis
Instabilities, Chromosomal
Infectious Mononucleosis
Malignant Tumor Of Colon
Aneuploidy
Myeloid Leukemia
Retroviridae Infections

Interacting Proteins

BIRC3
HLTF
LRSAM1
Map3k1
RBCK1

RFWD3
RNF11
RNF13
RNF168
RNF182

STUB1
Stub1
TRAF6
TRIM32
UBE2V1

UBE2V2
XIAP
ZNRF1

Pathways

Dna Repair
Conjugation
Translesion Synthesis
Postreplication Repair
Localization
Dna Replication
Osteoclast Differentiation
Hypersensitivity
Mitosis
Cell Death
Transport
Histone Ubiquitination
Regulation Of Signaling

Aging
Nuclear Export
Double-strand Break Repair
Spermatogenesis
Nuclear Transport
Interleukin-6 Production
Translation

PTMs

Ubiquitination
Phosphorylation
Sumoylation

Cleavage
Reduction
Isgylation

Acetylation

Research Areas

Cancer

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/UBE2N

References

PMID: 8902611 by Yamaguchi T., et al. Cloning and expression of cDNA encoding a human ubiquitin-conjugating enzyme similar to the Drosophila bendless gene product.

PMID: 16122702 by Zou W., et al. ISG15 modification of ubiquitin E2 Ubc13 disrupts its ability to form thioester bond with ubiquitin.