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- Table of Contents
2 Citations 17 Q&As
1 Citations 16 Q&As
Facts about Polyubiquitin-B.
Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair; Lys-11-linked is involved in ERAD (endoplasmic reticulum-associated degradation) and in cell-cycle regulation; Lys-29-linked is involved in lysosomal degradation; Lys-33-linked is involved in kinase modification; Lys-48-linked is involved in protein degradation via the proteasome; Lys-63-linked is involved in endocytosis, DNA-damage responses as well as in signaling processes leading to activation of the transcription factor NF-kappa-B. Linear polymer chains formed via attachment by the initiator Met lead to cell signaling.
Human | |
---|---|
Gene Name: | UBB |
Uniprot: | P0CG47 |
Entrez: | 7314 |
Belongs to: |
---|
ubiquitin family |
RPS27A; UBA52; UBB ubiquitin B; UBB; UBC; Ubiquitin
Mass (kDA):
25.762 kDA
Human | |
---|---|
Location: | 17p11.2 |
Sequence: | 17; NC_000017.11 (16380793..16382745) |
[Ubiquitin]: Cytoplasm. Nucleus.
Steven Boster and his research have been instrumental in the development of several gene infographics. Boster scientists can submit results on species, applications, and special samples to receive product credits. These credits are universally applicable and can be used by scientists all over the world. This article discusses a few of the ways Boster scientists use this marker in their work. Read on for more details. Here are some examples.
The Preley Family, a local nonprofit that supports artists and businesses in Texarkana, has been in operation for more than 100 years. The BBA, a nonprofit organization, was established in 1926 to bring quality arts to the community. Although many artists and craftspeople love the BBA for its rich history, Steven Boster uses UBB marker to make more beautiful creations.
PMID: 3029682 by Baker R.T., et al. The human ubiquitin gene family: structure of a gene and pseudogenes from the Ub B subfamily.
PMID: 14745543 by Tachikui H., et al. Lineage-specific homogenization of the polyubiquitin gene among human and great apes.
*More publications can be found for each product on its corresponding product page