UBAP1 Antibodies

AND UBAP1 ELISA kits, UBAP1 Proteins

Many biological assays use antibodies to detect UBAP1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with UBAP1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop UBAP1 antibodies...

We validate the specificity of these antibodies to UBAP1 by testing them on tissues known to express UBAP1 positively and negatively. Browse below to find the UBAP1 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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UBAP1 Infographic by Boster Bio

All UBAP1 Products

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Product

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Specificity

Applications

Price

Anti-Ubiquitin-associated protein 1 UBAP1 Antibody

Human, Mouse, Rat

ELISA, WB

$380
Cat # A08982
100ul

UBAP1 (NM_016525) Human Over-expression Lysate

Human

$628
Cat # LS051271
100 µg

UBAP1 Overview

Facts about Ubiquitin-associated protein 1.

UBAP1 3D structure. Source: alphafold

Ubiquitin-associated protein 1 (UBAP1)

Part of the ESCRT-I complicated, a regulator of vesicular trafficking procedure. Binds to ubiquitinated cargo proteins and is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs).

Plays a role in the proteasomal degradation of ubiquitinated cell-surface proteins, such as EGFR and BST2. .

Gene Information

Human
Gene Name:	UBAP1
Uniprot:	Q9NZ09
Entrez:	51271

Family

Belongs to:

No superfamily

Alternative Names

MGC119669; MGC8710; NAG20; Nasopharyngeal carcinoma-associated gene 20 protein; UAP; UBAP; UBAP-1; ubiquitin associated protein 1; ubiquitin associated protein; ubiquitin-associated protein 1

Molecular Weight

Mass (kDA):
55.084 kDA

Genomic Context


Human

Location:	9p13.3
Sequence:	9; NC_000009.12 (34179005..34252523)

Tissue Specificity

Ubiquitous. Highly expressed in heart, brain, placenta, lung, liver, skeletal muscle and pancreas.

Subcellular Localizations

Cytoplasm, cytosol. Endosome. Predominantly cytosolic (PubMed:21757351). Recruited to endosomes as part of the ESCRT-I complex (PubMed:21757351).

Diseases

Carcinoma
Neoplasms
Cancer Of Nasopharynx
Nasopharyngeal Neoplasms
Carcinogenesis
Dementia
Malignant Neoplasms
Cell Invasion
Frontotemporal Lobar Degeneration
Progressive Aphasia
Neoplasm Metastasis
Adult Acute Myeloblastic Leukemia
Neoplasm Invasiveness

Leukemia, Myelocytic, Acute
Cytogenetic Abnormality
Meningioma
Dysequilibrium Syndrome
Cell Transformation, Neoplastic
Frontotemporal Dementia
Malignant Paraganglionic Neoplasm

Interacting Proteins

PPIC

Pathways

Transport
Cell Cycle
Pathogenesis
Cytokinesis
Cell Proliferation
Ubiquitin Homeostasis
Membrane Invagination

Cell Growth
Endocytosis

PTMs

Ubiquitination

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/UBAP1

References

PMID: 11599797 by Qian J., et al. Isolation and characterization of a novel cDNA, UBAP1, derived from the tumor suppressor locus in human chromosome 9p21-22.

PMID: 21757351 by Stefani F., et al. UBAP1 is a component of an endosome-specific ESCRT-I complex that is essential for MVB sorting.