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- Table of Contents
Facts about Tumor suppressor candidate 2.
.
Human | |
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Gene Name: | TUSC2 |
Uniprot: | O75896 |
Entrez: | 11334 |
Belongs to: |
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TUSC2 family |
Tumor suppressor candidate 2
Mass (kDA):
12.074 kDA
Human | |
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Location: | 3p21.31 |
Sequence: | 3; NC_000003.12 (50324909..50328238, complement) |
Strong expression in heart, lung, skeletal muscle, kidney, and pancreas, followed by brain and liver, lowest levels in placenta.
PMID: 11593436 by Kondo M., et al. Overexpression of candidate tumor suppressor gene FUS1 isolated from the 3p21.3 homozygous deletion region leads to G1 arrest and growth inhibition of lung cancer cells.
PMID: 15126327 by Uno F., et al. Myristoylation of the fus1 protein is required for tumor suppression in human lung cancer cells.