Tau-tubulin kinase 1 Antibodies

AND TTBK1 ELISA kits, Tau-tubulin kinase 1 Proteins

Many biological assays use antibodies to detect Tau-tubulin kinase 1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Tau-tubulin kinase 1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Tau-tubulin kinase 1 antibodies...

We validate the specificity of these antibodies to Tau-tubulin kinase 1 by testing them on tissues known to express TTBK1 positively and negatively. Browse below to find the TTBK1 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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TTBK1 Infographic by Boster Bio

All TTBK1 Products

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Specificity

Applications

Price

Anti-Tau-tubulin kinase 1 TTBK1 Antibody

Human, Mouse

ELISA, IF, IHC-P, WB

$449
Cat # A09202
0.1 mg

TTBK1 (NM_032538) Human Over-expression Lysate

Human

$960
Cat # LS084630
100 µg

TTBK1 Overview

Facts about Tau-tubulin kinase 1.

TTBK1 3D structure. Source: alphafold

Tau-tubulin kinase 1 (TTBK1)

Serine/threonine kinase which is able to phosphorylate TAU on serine, threonine and tyrosine residues. Induces aggregation of TAU.

Gene Information

Human
Gene Name:	TTBK1
Uniprot:	Q5TCY1
Entrez:	84630

Family

Belongs to:

protein kinase superfamily

Alternative Names

BDTK; Brain-derived tau kinase; EC 2.7.11; EC 2.7.11.1; KIAA1855tau-tubulin kinase 1; RP3-330M21.4; tau tubulin kinase 1

Molecular Weight

Mass (kDA):
142.737 kDA

Genomic Context


Human

Location:	6p21.1
Sequence:	6; NC_000006.12 (43243481..43288259)

Tissue Specificity

Expressed in the brain, particularly in cortical and hippocampal neurons. Weakly expressed in spinal cord and testis. No expression in adipose tissue, bladder, cervix, colon, esophagus, heart, kidney, liver, lung, ovary, placenta, prostate, skeletal muscle, small intestine, spleen, testis, thymus, thyroid or trachea.

Subcellular Localizations

Cytoplasm.

Diseases

Alzheimer's Disease
Tauopathies
Neurofibrillary Tangles
Nerve Degeneration
Sclerosis
Neuroblastoma
Learning Disorders
Brain Ischemia
Primary Lateral Sclerosis
Ischemia
Traumatic Brain Injury
Neurodegenerative Disorders

Multiple Sclerosis
Amyotrophic Lateral Sclerosis
Memory Impairment
Huntington Disease
Dysequilibrium Syndrome
Motor Skills Disorders
Brain Injuries

Pathways

Pathogenesis
Protein Phosphorylation
Cell Division
Hyperphosphorylation
Cell Cycle
Regulation Of Cell Division

PTMs

Phosphorylation

Research Areas

Protein Kinase

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TTBK1

References

PMID: 16923168 by Sato S., et al. Tau-tubulin kinase 1 (TTBK1), a neuron-specific tau kinase candidate, is involved in tau phosphorylation and aggregation.