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- Table of Contents
3 Citations 9 Q&As
1 Citations 7 Q&As
Facts about Tumor necrosis factor receptor superfamily member 8.
Receptor for TNFSF8/CD30L.
May play a role in the regulation of cellular growth and transformation of activated lymphoblasts.Regulates gene expression through activation of NF- kappa-B. .
Human | |
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Gene Name: | TNFRSF8 |
Uniprot: | P28908 |
Entrez: | 943 |
Belongs to: |
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TNFR8 family |
CD30 antigen; CD30; CD30KI-1; CD30L receptor; cytokine receptor CD30; D1S166EKi-1; Ki-1 antigen; Lymphocyte activation antigen CD30; TNFRSF8; tumor necrosis factor receptor superfamily member 8; tumor necrosis factor receptor superfamily, member 8
Mass (kDA):
63.747 kDA
Human | |
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Location: | 1p36.22 |
Sequence: | 1; NC_000001.11 (12063303..12144213) |
[Isoform 1]: Cell membrane; Single-pass type I membrane protein.; [Isoform 2]: Cytoplasm.
PMID: 1310894 by Duerkop H., et al. Molecular cloning and expression of a new member of the nerve growth factor receptor family that is characteristic for Hodgkin's disease.
PMID: 7527901 by Jung W., et al. Opposite effects of the CD30 ligand are not due to CD30 mutations: results from cDNA cloning and sequence comparison of the CD30 antigen from different sources.
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