Toll-like receptor 5 Antibodies

AND TLR5 ELISA kits, Toll-like receptor 5 Proteins

Many biological assays use antibodies to detect Toll-like receptor 5, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Toll-like receptor 5 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Toll-like receptor 5 antibodies...

We validate the specificity of these antibodies to Toll-like receptor 5 by testing them on tissues known to express TLR5 positively and negatively. Browse below to find the TLR5 antibody that suites your experiment. We have 6 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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TLR5 Infographic by Boster Bio

All TLR5 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-TLR5 Antibody Picoband®

6 Q&As

Human

Flow Cytometry, IHC, ICC, WB

$370
Cat # PB9451
100 μg/vial

Anti-TLR5 Rabbit Monoclonal Antibody

Human, Mouse, Rat

$370
Cat # M00462
100 μl

Anti-Toll-like receptor 5 TLR5 Antibody

Human, Mouse, Rat

ELISA, IHC-P, WB

$449
Cat # A00462
0.1 mg

Anti-Toll-like receptor 5 TLR5 Antibody

Human, Mouse

ELISA, IF, ICC, WB

$449
Cat # A00462-1
0.1 mg

Anti-Tlr5 Antibody Picoband®

Mouse, Rat

ELISA, WB

$370
Cat # A00462-2
100 μg/vial

TLR5 (NM_003268) Human Over-expression Lysate

Human

$960
Cat # LS007100
100 µg

TLR5 Overview

Facts about Toll-like receptor 5.

TLR5 3D structure. Source: alphafold

Toll-like receptor 5 (TLR5)

Participates in the innate immune response to microbial agents. Mediates detection of bacterial flagellins.

Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. .

Gene Information

Human
Gene Name:	TLR5
Uniprot:	O60602
Entrez:	7100

Family

Belongs to:

Toll-like receptor family

Alternative Names

MGC126430; MGC126431; SLEB1FLJ10052; TIL-3; TIL3Toll/interleukin-1 receptor-like protein 3; TLR5; toll-like receptor 5

Molecular Weight

Mass (kDA):
97.834 kDA

Genomic Context


Human

Location:	1q41
Sequence:	1; NC_000001.11 (223108401..223143281, complement)

Tissue Specificity

Highly expressed in ovary and in peripheral blood leukocytes, especially in monocytes, less in CD11c+ immature dendritic cells. Also detected in prostate and testis.

Subcellular Localizations

Cell membrane; Single-pass type I membrane protein.

Diseases

Inflammation
Innate Immune Response
Salmonella Infections
Infective Disorder
Inflammatory Response
Pneumonia
Bacterial Infections
Malignant Neoplasms
Neoplasms
Colitis
Systemic Infection
Intestinal Diseases
Influenza

Ulcer
Pseudomonas Infections
Crohn Disease
Inflammatory Bowel Diseases
Salmonella Infections, Animal
Tissue Adhesions
Fibrosis

Pathways

Immune Response
Secretion
Innate Immune Response
Cytokine Production
Pathogenesis
Inflammatory Response
Cell Activation
Cell Proliferation
Localization
Adaptive Immune Response
Phagocytosis
Chemokine Production
Virulence

Chemokine Secretion
Aging
Cell Death
Reverse Transcription
Transport
Cytokine Secretion
Response To Lipopolysaccharide

PTMs

Phosphorylation
Methylation
Cleavage
Glycosylation
Biotinylation

Nitration
Reduction
Dephosphorylation
Acylation
Myristoylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TLR5

References

PMID: 9596645 by Chaudhary P.M., et al. Cloning and characterization of two Toll/Interleukin-1 receptor-like genes TIL3 and TIL4: evidence for a multi-gene receptor family in humans.

PMID: 18810425 by Nakajima T., et al. Natural selection in the TLR-related genes in the course of primate evolution.