TIMP1 Antibodies

AND TIMP1 ELISA kits, TIMP1 Proteins

Many biological assays use antibodies to detect TIMP1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TIMP1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TIMP1 antibodies...

We validate the specificity of these antibodies to TIMP1 by testing them on tissues known to express TIMP1 positively and negatively. Browse below to find the TIMP1 antibody that suites your experiment. We have 13 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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TIMP1 Infographic by Boster Bio

All TIMP1 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Human TIMP-1 ELISA Kit PicoKine®

30 Citations 10 Q&As

Human

ELISA

$499
Cat # EK0520
96 wells/kit, with removable strips.

Mouse TIMP-1 ELISA Kit PicoKine®

21 Citations 7 Q&As

Mouse

ELISA

$499
Cat # EK0521
96 wells/kit, with removable strips.

Rat TIMP-1 ELISA Kit PicoKine®

12 Citations 10 Q&As

Rat

ELISA

$499
Cat # EK0583
96 wells/kit, with removable strips.

Anti-Metalloproteinase inhibitor 1 TIMP1 Antibody Picoband®

23 Citations 6 Q&As

Human

IHC, WB

$370
Cat # PA1385
100 μg/vial

Anti-TIMP1 Antibody Picoband®

25 Citations

Human, Mouse, Rat

ELISA, WB

$370
Cat # A00561
100 μg/vial

Anti-TIMP1 Rabbit Monoclonal Antibody

4 Citations

Human

IHC, WB

$370
Cat # M00561-1
100 μl

Anti-TIMP1 Rabbit Monoclonal Antibody

6 Citations

Human

IF, IHC, ICC, WB

$370
Cat # M00561
100 μl

Human TIMP-1 PicoKine® Quick ELISA Kit

3 Citations 1 Q&As

Human

ELISA

$499
Cat # FEK0520
96 wells/kit, with removable strips.

Anti-TIMP1 Antibody Picoband®

5 Citations

Human, Mouse, Rat

ELISA, WB

$370
Cat # A00561-1
100 μg/vial

Anti-TIMP1 Antibody Picoband®

Mouse, Rat

ELISA, Flow Cytometry, WB

$370
Cat # A00561-2
100 μg/vial

Human TIMP-1 Recombinant Protein

SDS-PAGE

$250
Cat # PROTP01033
Starting from 10ug

Rat TIMP-1 Recombinant Protein

SDS-PAGE

$250
Cat # PROTP30120
Starting from 10ug

TIMP1 (NM_003254) Human Over-expression Lysate

Human

$628
Cat # LS007076
100 µg

TIMP1 Overview

Facts about Metalloproteinase inhibitor 1.

TIMP1 3D structure. Source: alphafold

Metalloproteinase inhibitor 1 (TIMP1)

Metalloproteinase inhibitor that works by forming one to one complexes with target metalloproteinases, like collagenases, and irreversibly inactivates them by binding to their catalytic zinc cofactor. Founded on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP13 and MMP16.

Does not act on MMP14. Also functions as a growth factor that regulates cell differentiation, migration and cell death and activates cellular signaling cascades through CD63 and ITGB1.

Gene Information

Human
Gene Name:	TIMP1
Uniprot:	P01033
Entrez:	7076

Family

Belongs to:

protease inhibitor I35 (TIMP) family

Alternative Names

CLGI; Collagenase inhibitor; collagenase inhibitor); EPATIMP-1; EPO; erythroid potentiating activity; Erythroid-potentiating activity; Fibroblast collagenase inhibitor; FLJ90373; HCI; metalloproteinase inhibitor 1; TIMP metallopeptidase inhibitor 1; TIMP1; TIMP-1; TIMPtissue inhibitor of metalloproteinase 1 (erythroid potentiating activity; Tissue inhibitor of metalloproteinases 1

Molecular Weight

Mass (kDA):
23.171 kDA

Genomic Context


Human

Location:	Xp11.3
Sequence:	X; NC_000023.11 (47582408..47586789)

Tissue Specificity

Detected in rheumatoid synovial fluid (at protein level).

Subcellular Localizations

Secreted.

Diseases

Malignant Neoplasms
Neoplasms
Cell Invasion
Fibrosis
Inflammation
Neoplasm Metastasis
Carcinoma
Neoplasm Invasiveness
Tissue Adhesions
Tumor Angiogenesis
Hepatic Fibrosis
Malignant Paraganglionic Neoplasm
Lung Neoplasms

Hyperplasia
Liver Cirrhosis
Malignant Neoplasm Of Lung
Mammary Neoplasms
Degenerative Polyarthritis
Malignant Neoplasm Of Breast
Malignant Squamous Cell Neoplasm

Interacting Proteins

CD63
CD82
COL5A1
MMP9

Pathways

Pathogenesis
Angiogenesis
Secretion
Cell Proliferation
Localization
Wound Healing
Tissue Remodeling
Cell Adhesion
Cell Migration
Regeneration
Cell Cycle
Cell Growth
Reverse Transcription

Inflammatory Response
Immune Response
Cell Death
Cell Motility
Proteolysis
Ovulation
Transport

PTMs

Phosphorylation
Cleavage
Methylation
Glycosylation
Acetylation
Demethylation

Reduction
Oxidation
Nitration
Dephosphorylation
Prenylation
Acylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TIMP1

References

PMID: 3903517 by Docherty A.J.P., et al. Sequence of human tissue inhibitor of metalloproteinases and its identity to erythroid-potentiating activity.

PMID: 3839290 by Gasson J.C., et al. Molecular characterization and expression of the gene encoding human erythroid-potentiating activity.

87 Publications of Boster TIMP1 Antibodies & ELISA Kits

PubMed ID: 10.3892/mmr.2020.11055, 4,4‑Bond secalonic acid D targets SP cells and inhibits metastasis in hepatoce...
PubMed ID: 10.3892/mmr.2018.8542, LPS‑induced proinflammatory cytokine expression in human airway epithelial cel...
PubMed ID: 10.3892/etm.2015.2194, Decreased expression of matrix metalloproteinase-1 in the maternal umbilical ser...
PubMed ID: 10.3390/molecules26216575, Anti-Cancer Properties of Ginkgolic Acids in Human Nasopharyngeal Carcinoma CNE-...
PubMed ID: 10.3233/THC-218020, H2S improves doxorubicin-induced myocardial fibrosis by inhibiting oxidative str...
PubMed ID: 10.3233/CH-151928, Gelatinases and their tissue inhibitors in a group of subjects with obstructive ...
PubMed ID: 10.3233/CH-141863, Behaviour of the plasma concentration of gelatinases and their tissue inhibitors...
PubMed ID: 10.3109/15368378.2016.1140058, Effects of electromagnetic pulse exposure on gelatinase of blood–brain barrier...
PubMed ID: 10.3109/13880200903046211, Effects of pearl powder extract and its fractions on fibroblast function relevan...
PubMed ID: 10.2310/JIM.0b013e318294e9da, Gelatinases and Their Tissue Inhibitors in a Group of Subjects With Metabolic Sy...
PubMed ID: 10.2147/CMAR.S233776, MMP-2, MMP-9, TIMP-1, and TIMP-2 in the Peripheral Blood of Patients with Differ...
PubMed ID: 10.18632/oncotarget.9949, Crucial factors of the inflammatory microenvironment (IL-1β/TNF-α/TIMP-1) prom...
PubMed ID: 10.1507/endocrj.EJ17-0445, Hydrogen sulfide ameliorates rat myocardial fibrosis induced by thyroxine throug...
PubMed ID: 10.1186/s12985-014-0230-z, IL-22-producing Th22 cells play a protective role in CVB3-induced chronic myocar...
PubMed ID: 10.1177/0885328216688337, Evaluation on biological compatibility of carboxymethyl chitosan as biomaterials...
PubMed ID: 10.1155/2020/4260204, Exposure to Air Pollution Exacerbates Inflammation in Rats with Preexisting COPD
PubMed ID: 10.1111/j.1600-0714.2008.00738.x, Influence of borneol on primary mice oral fibroblasts: a penetration enhancer ma...
PubMed ID: 10.1111/eos.12625, Modulatory effect of curcumin analogs on the activation of metalloproteinases in...
PubMed ID: 10.1038/s41419-018-0527-8, LincRNA 1700020I14Rik alleviates cell proliferation and fibrosis in diabetic nep...
PubMed ID: 10.1021/acsbiomaterials.6b00618, Evaluation of the Size-Dependent Cytotoxicity of DLC (Diamondlike Carbon) Wear D...
PubMed ID: 10.1016/S0254-6272(10)60028-3, Regulatory Action of Charred Gossamer Urocteae on the Functions of Mouse Oral Fi...

*Showing only the more recent 20. More publications can be found for each product on its corresponding product page