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- Table of Contents
, No Gclids
TFPI Antibodies
AND TFPI ELISA kits, TFPI Proteins
Many biological assays use antibodies to detect TFPI, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TFPI in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TFPI antibodies...
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TFPI Infographic by Boster Bio
All TFPI Products
Product
Figures
Specificity
Applications
Price
Human TFPI / Tissue Factor Pathway Inhibitor ELISA Kit PicoKine®
1 Citations 11 Q&As
Human
ELISA
$499
Cat # EK0840
96 wells/kit, with removable strips.
Cat # EK0840
96 wells/kit, with removable strips.
Mouse
ELISA
$499
Cat # EK1355
96 wells/kit, with removable strips.
Cat # EK1355
96 wells/kit, with removable strips.
Mouse
ELISA
$499
Cat # FEK1355
96 wells/kit, with removable strips.
Cat # FEK1355
96 wells/kit, with removable strips.
TFPI Overview
Facts about Tissue factor pathway inhibitor.
Tissue factor pathway inhibitor (TFPI)
Inhibits factor X (X(a)) directly and, in a Xa-dependent manner, inhibits VIIa/tissue factor activity, presumably by forming a quaternary Xa/LACI/VIIa/TF complex. It owns an antithrombotic action and also the capability to connect with lipoproteins in plasma.
.
Gene Information
| Human | |
|---|---|
| Gene Name: | TFPI |
| Uniprot: | P10646 |
| Entrez: | 7035 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
convertin; EPI; EPITFPI1LACITFI; Extrinsic pathway inhibitor; LACI; Lipoprotein-associated coagulation inhibitor; TFPI; tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor); tissue factor pathway inhibitor
Molecular Weight
Mass (kDA):
35.015 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 2q32.1 |
| Sequence: | 2; NC_000002.12 (187464230..187554505, complement) |
Tissue Specificity
Mostly in endothelial cells.
Subcellular Localizations
[Isoform Alpha]: Secreted.; [Isoform Beta]: Microsome membrane; Lipid-anchor, GPI-anchor.
Diseases
- Thrombosis
- Blood Coagulation Disorders
- Thrombophilia
- Inflammation
- Hemorrhage
- Venous Thrombosis
- Neoplasms
- Malignant Neoplasms
- Systemic Infection
- Thrombus
- Von Willebrand Disease
- Disseminated Intravascular Coagulation
- Infarction
Pathways
- Coagulation
- Blood Coagulation
- Fibrinolysis
- Hemostasis
- Pathogenesis
- Angiogenesis
- Localization
- Secretion
- Cell Proliferation
- Platelet Activation
- Proteolysis
- Inflammatory Response
- Platelet Aggregation
PTMs
- Cleavage
- Phosphorylation
- Glycosylation
- Oxidation
- Gpi Anchoring
- Reduction
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TFPI
bosterbio.com/bosterbio-gene-info-cards/TFPI
References
PMID: 2452157 by Wun T.-C., et al. Cloning and characterization of a cDNA coding for the lipoprotein- associated coagulation inhibitor shows that it consists of three tandem Kunitz-type inhibitory domains.
PMID: 2781520 by Girard T.J., et al. Identification of the 1.4 kb and 4.0 kb messages for the lipoprotein associated coagulation inhibitor and expression of the encoded protein.
1 Publications of Boster TFPI Antibodies & ELISA Kits
- PubMed ID: 22866126, Xu Y, Qin X, Zhou J, Tu Z, Bi X, Li W, Fan X, Zhang Y. Oncol Lett. 2011 Sep 1;2(...
*More publications can be found for each product on its corresponding product page