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- Table of Contents
Facts about Thyroglobulin.
Human | |
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Gene Name: | TG |
Uniprot: | P01266 |
Entrez: | 7038 |
Belongs to: |
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type-B carboxylesterase/lipase family |
AITD3; AITD3TGN; cog; TDH3; Tg; TGN; Thyroglobulin
Mass (kDA):
304.79 kDA
Human | |
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Location: | 8q24.22 |
Sequence: | 8; NC_000008.11 (132866943..133134902) |
Thyroid gland specific.
Secreted. Secreted into the thyroid follicle lumen (PubMed:19509106). Localizes to colloid globules, a structure formed in the thyroid follicle lumen consisting of cross-linked TG arranged in concentric layers (PubMed:8626858, PubMed:11082042).
PMID: 3595599 by Malthiery Y., et al. Primary structure of human thyroglobulin deduced from the sequence of its 8448-base complementary DNA.
PMID: 9186272 by van de Graaf S.A.R., et al. The revised 8307 base pair coding sequence of human thyroglobulin transiently expressed in eukaryotic cells.