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- Table of Contents
Facts about Transcription initiation factor TFIID subunit 4B.
TAF4B is a transcriptional coactivator of the p65/RELA NF-kappa-B subunit. Involved in the activation of a subset of antiapoptotic genes such as TNFAIP3.
Human | |
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Gene Name: | TAF4B |
Uniprot: | Q92750 |
Entrez: | 6875 |
Belongs to: |
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TAF4 family |
Transcription initiation factor TFIID subunit 4B
Mass (kDA):
91.091 kDA
Human | |
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Location: | 18q11.2 |
Sequence: | 18; NC_000018.10 (26226445..26391685) |
Preferentially expressed in ovarian granulosa cells (at protein level). Highly expressed in B-cells.
Nucleus. Cytoplasm. Export into the cytoplasm is mediated by a CRM1-independent nuclear export pathway and not by phosphorylation.
PMID: 16088961 by Wu Y., et al. Cyclic AMP-dependent modification of gonad-selective TAF(II)105 in a human ovarian granulosa cell line.
PMID: 8858156 by Dikstein R., et al. Human TAFII 105 is a cell type-specific TFIID subunit related to hTAFII130.