Transcriptional adapter 3 Antibodies

AND TADA3 ELISA kits, Transcriptional adapter 3 Proteins

Many biological assays use antibodies to detect Transcriptional adapter 3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Transcriptional adapter 3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Transcriptional adapter 3 antibodies...

We validate the specificity of these antibodies to Transcriptional adapter 3 by testing them on tissues known to express TADA3 positively and negatively. Browse below to find the TADA3 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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TADA3 Infographic by Boster Bio

All TADA3 Products

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Product

Figures

Specificity

Applications

Price

Anti-TADA3L Antibody

Human, Mouse, Rat

IF, ICC, WB

$405
Cat # A06445
100ul

TADA3L (TADA3) (NM_006354) Human Recombinant Protein

$813
Cat # PROTO75528
20 µg

TADA3L (TADA3) (NM_006354) Human Over-expression Lysate

Human

$628
Cat # LS010474
100 µg

TADA3 Overview

Facts about Transcriptional adapter 3.

TADA3 3D structure. Source: alphafold

Transcriptional adapter 3 (TADA3)

Functions as a component of the PCAF complex.
The PCAF complex is capable of efficiently acetylating histones in a nucleosomal context.

The PCAF complex could be regarded as the human version of the yeast SAGA complex. Also called a coactivator for p53/TP53-dependent transcriptional activation.

Gene Information

Human
Gene Name:	TADA3
Uniprot:	O75528
Entrez:	10474

Family

Belongs to:

NGG1 family

Alternative Names

ADA3ADA3 homolog; FLJ20221; FLJ21329; hADA3ADA3-like protein; NGG1; STAF54; TADA3Ltranscriptional adaptor 3 (NGG1 homolog, yeast)-like; transcriptional adapter 3; Transcriptional adapter 3-like; transcriptional adaptor 3

Molecular Weight

Mass (kDA):
48.902 kDA

Genomic Context


Human

Location:	3p25.3
Sequence:	3; NC_000003.12 (9779964..9793011, complement)

Tissue Specificity

Ubiquitously expressed.

Subcellular Localizations

Nucleus.

Diseases

Malignant Neoplasms
Cell Transformation, Neoplastic
Neoplasms
Carcinoma
Papilloma
Malignant Neoplasm Of Breast
Uterine Cervical Neoplasm
Malignant Paraganglionic Neoplasm
Malignant Tumor Of Cervix
Hypokinesia

Congenital Heart Defects
Mammary Neoplasms
Genotoxic Stress
Hyperplasia
Growth Arrest

Interacting Proteins

AATF
CCNC
Dclk3
HEXIM2
PIAS4

SGF29
USP5

Pathways

Cell Cycle
Oncogenesis
Senescence
Rna Interference
Cell Cycle Arrest
Cell Proliferation
Protein Acetylation
S Phase

Histone Acetylation
Tissue Homeostasis
Chromatin Remodeling

PTMs

Acetylation

Phosphorylation

Research Areas

Cell Cycle and Replication

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TADA3

References

PMID: 9674425 by Ogryzko V.V., et al. Histone-like TAFs within the PCAF histone acetylase complex.

PMID: 11564863 by Martinez E., et al. Human STAGA complex is a chromatin-acetylating transcription coactivator that interacts with pre-mRNA splicing and DNA damage- binding factors in vivo.