Taar1 Antibodies

AND Taar1 ELISA kits, Taar1 Proteins

Many biological assays use antibodies to detect Taar1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Taar1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Taar1 antibodies...

We validate the specificity of these antibodies to Taar1 by testing them on tissues known to express Taar1 positively and negatively. Browse below to find the Taar1 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Taar1 Infographic by Boster Bio

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Anti-TAAR1 Antibody

Human, Mouse, Rat

$405
Cat # A07105
100ul

Taar1 Overview

Facts about Trace amine-associated receptor 1.

Trace amine-associated receptor 1 (Taar1)

Receptor for trace amines, including beta- phenylethylamine (b-PEA), p-tyramine (p-TYR), octopamine and tryptamine, with highest affinity for b-PEA and p-TYR. Unresponsive to classical biogenic amines, such as epinephrine and histamine and only partially activated by serotonin and dopamine.

Trace amines are biogenic amines present in very low levels in mammalian tissues. While some trace amines have clearly defined roles as neurotransmitters in invertebrates, the extent to which they function as true neurotransmitters in vertebrates has remained speculative.

Gene Information

Mouse
Gene Name:	Taar1
Uniprot:	Q923Y8
Entrez:	111174

Family

Belongs to:

G-protein coupled receptor 1 family

Alternative Names

MGC126874; MGC138399; TA1RP11-295F4.9; TaR-1; TAR1trace amine-associated receptor 1; trace amine associated receptor 1; Trace amine receptor 1taR-1; TRAR1

Molecular Weight

Mass (kDA):
37.621 kDA

Genomic Context


Mouse

Location:	10\|10 A4
Sequence:	10;

Tissue Specificity

Widely distributed throughout the brain. Strongly expressed in the mitral cell layer of the olfactory bulb, piriform cortex, the arcuate, motor, and mesencephalic trigeminal nuclei, lateral reticular and hypoglossal nuclei, cerebellar Purkinje cells, and ventral horn of the spinal cord. Moderately expressed in the frontal, entorhinal, and agranular cortices, the ventral pallidum, thalamus, hippocampus, several hypothalamic nuclei, ambiguus, dorsal raphe, and gigantocellular reticular nuclei. Weakly expressed in the septum, basal ganglia, amygdala, myelencephalon, and spinal cord dorsal horn. Particularly interesting is the moderate expression in several monoaminergic cell groups, namely the dorsal raphe, the locus coeruleus, and the ventral tegmental area.

Diseases

Schizophrenia
Nervousness
Parkinson Disease
Nervous System Disorder
Mood Disorders
Bipolar Disorder
Burkitt Lymphoma
Malnutrition
Cardiac Arrhythmia
Neurodegenerative Disorders
Thyroid Diseases
Dyskinetic Syndrome

Malignant Neoplasms
Asthma
Pain
Hyperglycemia
Attention Deficit Hyperactivity Disorder
Pertussis

Pathways

Dopamine Uptake
Bioluminescence
Insulin Secretion
Locomotion
Cognition
Secretion
Transport
Regulation Of Energy Homeostasis
Prepulse Inhibition
Glycosylation
Immune Response

Energy Homeostasis
Serotonin Uptake
Localization
Sensitization
Excretion

PTMs

Phosphorylation
Decarboxylation
Biotinylation

Deiodination
Carboxylation
Glycosylation

Research Areas

GPCR

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Taar1

References

PMID: 11459929 by Borowsky B., et al. Trace amines: identification of a family of mammalian G protein- coupled receptors.

PMID: 15718104 by Lindemann L., et al. Trace amine-associated receptors form structurally and functionally distinct subfamilies of novel G protein-coupled receptors.