TUT7 Antibodies

AND TUT7 ELISA kits, TUT7 Proteins

Many biological assays use antibodies to detect TUT7, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TUT7 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TUT7 antibodies...

We validate the specificity of these antibodies to TUT7 by testing them on tissues known to express TUT7 positively and negatively. Browse below to find the TUT7 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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TUT7 Infographic by Boster Bio

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TUT7 (NM_024617) Human Over-expression Lysate

Human

$960
Cat # LS079670
100 µg

TUT7 Overview

Facts about Terminal uridylyltransferase 7.

TUT7 3D structure. Source: alphafold

Terminal uridylyltransferase 7 (TUT7)

Uridylyltransferase that mediates the terminal uridylation of mRNAs with short (less than 25 nucleotides) poly(A) tails, hence facilitating international mRNA decay (PubMed:19703396, PubMed:25480299). Essential for both oocyte maturation and fertility.

During 3' terminal uridylation of mRNA, sculpts, with TUT7, the maternal transcriptome by removing transcripts during oocyte growth (By similarity). Involved in microRNA (miRNA)- triggered gene silencing through uridylation of deadenylated miRNA targets (PubMed:25480299).

Gene Information

Human
Gene Name:	TUT7
Uniprot:	Q5VYS8
Entrez:	79670

Family

Belongs to:

DNA polymerase type-B-like family

Alternative Names

Terminal uridylyltransferase 7

Molecular Weight

Mass (kDA):
171.229 kDA

Genomic Context


Human

Location:	9q21.33
Sequence:	9; NC_000009.12 (86287733..86354497, complement)

Subcellular Localizations

Cytoplasm. Expression is pancytoplasmic in contrast with TUT4 expression which is enriched in cytoplasmic ribonucleoprotein granules.

PTMs

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TUT7

References

PMID: 18172165 by Mullen T.E., et al. Degradation of histone mRNA requires oligouridylation followed by decapping and simultaneous degradation of the mRNA both 5' to 3' and 3' to 5'.

PMID: 17353264 by Rissland O.S., et al. Efficient RNA polyuridylation by noncanonical poly(A) polymerases.