Tubby-related protein 3 Antibodies

AND TULP3 ELISA kits, Tubby-related protein 3 Proteins

Many biological assays use antibodies to detect Tubby-related protein 3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Tubby-related protein 3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Tubby-related protein 3 antibodies...

We validate the specificity of these antibodies to Tubby-related protein 3 by testing them on tissues known to express TULP3 positively and negatively. Browse below to find the TULP3 antibody that suites your experiment. We have 6 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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TULP3 Infographic by Boster Bio

All TULP3 Products

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Specificity

Applications

Price

TULP3 (NM_003324) Human Recombinant Protein

$813
Cat # PROTO75386
20 µg

Anti-TULP3 Mouse Monoclonal Antibody [Clone ID: OTI1A10]

Dog, Human, Mouse

$523
Cat # M09384-1
100 µl

Anti-TULP3 Mouse Monoclonal Antibody [Clone ID: OTI4E5]

Human

IF, IHC, WB

$523
Cat # M09384
100 µl

Anti-TULP3 Mouse Monoclonal Antibody [Clone ID: OTI7B8]

Human

Flow Cytometry, IF, IHC, WB

$523
Cat # M09384-2
100 µl

TULP3 (NM_003324) Human Over-expression Lysate

Human

$628
Cat # LS007289
100 µg

Anti-TULP3 Antibody Picoband®

Human

ELISA, WB

$370
Cat # A09384-2
100 μg/vial

TULP3 Overview

Facts about Tubby-related protein 3.

TULP3 3D structure. Source: alphafold

Tubby-related protein 3 (TULP3)

Negative regulator of the Shh signaling transduction pathway: recruited to primary cilia via association with the IFT complex A (IFT-A) and is necessary for recruitment of G protein- coupled receptor GPR161 into cilia, a promoter of PKA-dependent basal repression machinery in Shh signaling. Binds to phosphorylated inositide (phosphoinositide) lipids.

The two IFT- A- and phosphoinositide-binding properties are required to regulate ciliary G protein-coupled receptor trafficking. Not involved in ciliogenesis.

Gene Information

Human
Gene Name:	TULP3
Uniprot:	O75386
Entrez:	7289

Family

Belongs to:

TUB family

Alternative Names

MGC45295; tubby like protein 3; tubby-related protein 3; TUBL3Tubby-like protein 3

Molecular Weight

Mass (kDA):
49.642 kDA

Genomic Context


Human

Location:	12p13.33
Sequence:	12; NC_000012.12 (2890891..2941138)

Tissue Specificity

Expressed at high levels in testis, ovaries, thyroid, and spinal chord.

Subcellular Localizations

Nucleus. Cell membrane. Cell projection, cilium. Cytoplasm. Secreted. Does not have a cleavable signal peptide and is secreted by a non-conventional pathway (By similarity). Translocates from the plasma membrane to the nucleus upon activation of guanine nucleotide-binding protein G(q) subunit alpha.