Tubulin beta-3 chain Antibodies

AND TUBB3 ELISA kits, Tubulin beta-3 chain Proteins

Many biological assays use antibodies to detect Tubulin beta-3 chain, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Tubulin beta-3 chain in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Tubulin beta-3 chain antibodies...

We validate the specificity of these antibodies to Tubulin beta-3 chain by testing them on tissues known to express TUBB3 positively and negatively. Browse below to find the TUBB3 antibody that suites your experiment. We have 6 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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TUBB3 Infographic by Boster Bio

All TUBB3 Products

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Product

Figures

Specificity

Applications

Price

Anti-beta Tubulin Rabbit Monoclonal Antibody, HRP Conjugated

Human, Mouse, Rat

$370
Cat # H01857
100 μl

Anti-beta III Tubulin TUBB3 Rabbit Monoclonal Antibody

1 Citations 1 Q&As

Human, Mouse, Rat

IP, IF, IHC, ICC, WB

$370
Cat # M01857
100 μl

Anti-beta III Tubulin TUBB3 Rabbit Monoclonal Antibody

2 Citations 4 Q&As

Human, Mouse, Rat

Flow Cytometry, IP, IF, IHC, ICC, WB

$370
Cat # M01857-1
100 μl

Tubulin beta Colorimetric Cell-Based ELISA Kit

Human, Mouse, Rat

ELISA

$480
Cat # EKC1581
1 kit, containing one 96-well plate and all necessary reagents

Human TuBB3 Recombinant Protein

SDS-PAGE

$265
Cat # PROTQ13509
Starting from 10ug

beta III Tubulin (TUBB3) (NM_006086) Human Over-expression Lysate

Human

$628
Cat # LS010381
100 µg

TUBB3 Overview

Facts about Tubulin beta-3 chain.

TUBB3 3D structure. Source: alphafold

Tubulin beta-3 chain (TUBB3)

Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.

TUBB3 plays a crucial role in proper axon guidance and mantainance. .

Gene Information

Human
Gene Name:	TUBB3
Uniprot:	Q13509
Entrez:	10381

Family

Belongs to:

tubulin family

Alternative Names

Beta3-tubulin; beta-4; betaIII Tubulin; beta-III Tubulin; beta-Tubulin III; Class III beta-tubulin; TUBB3; TUBB4 CFEOM3A; Tubulin Beta 3; tubulin beta-3 chain; Tubulin beta-4 chain; Tubulin beta-4; Tubulin beta-III; tubulin, beta 3; TUJ1 antigen; TUJ-1 antigen

Molecular Weight

Mass (kDA):
50.433 kDA

Genomic Context


Human

Location:	16q24.3
Sequence:	16; NC_000016.10 (89921925..89936097)

Tissue Specificity

Expression is primarily restricted to central and peripheral nervous system. Greatly increased expression in most cancerous tissues.

Subcellular Localizations

Cytoplasm, cytoskeleton. Cell projection, lamellipodium. Cell projection, filopodium.

Diseases

Malignant Neoplasms
Neoplasms
Malignant Neoplasm Of Lung
Non-small Cell Lung Carcinoma
Malignant Neoplasm Of Ovary
Lung Neoplasms
Ovarian Neoplasm
Carcinoma
Nervousness
Fibrosis
Hypoxia
Hypoplasia
Nervous System Disorder

Adenocarcinoma
Neoplasm Metastasis
Malignant Neoplasm Of Breast
Cell Transformation, Neoplastic
Malignant Paraganglionic Neoplasm
Lissencephaly
Tumor Progression

Interacting Proteins

TERF1
TUBA1B
UNC5C

Pathways

Cell Cycle
Drug Resistance
Axon Guidance
Localization
Neurogenesis
Methylation
Cell Proliferation
Regeneration
Response To Paclitaxel
Spermatogenesis
Cell Division
Transport
Gene Silencing

Brain Development
System Development
Cell Death
Nervous System Development
Cell Adhesion
Cell Migration
Axon Regeneration

PTMs

Methylation
Demethylation
Acetylation

Phosphorylation
Deacetylation
Glycosylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TUBB3

References

PMID: 9473684 by Ranganathan S., et al. Cloning and sequencing of human betaIII-tubulin cDNA: induction of betaIII isotype in human prostate carcinoma cells by acute exposure to antimicrotubule agents.

PMID: 14736079 by Katsetos C.D., et al. Class III beta-tubulin isotype: a key cytoskeletal protein at the crossroads of developmental neurobiology and tumor neuropathology.

9 Publications of Boster Tubulin beta-3 chain Antibodies & ELISA Kits

PubMed ID: 10.1021/acschemneuro.0c00052, Mesenchymal Stem Cells Could Be Considered as a Candidate for Further Studies in...
PubMed ID: 30554401, Shen X,Zhang J,Zhang X,Wang Y,Hu Y,Guo J.Retinoic Acid-Induced Protein 14 (RAI14...
PubMed ID: -, Han Zhang,Huaishan Wang,Fei Gao,Jia Yang,Yi Xu,Yi Fu,Menghua Cai,Xue Zhang,Qi Ya...
PubMed ID: -, Yu Jiao,Ran Hu,Sirong Hu,Binge Wang,Dehong Huang,Zhou Lan,Shenrong Wuzi Pill aff...
PubMed ID: -, Shi,W.,Que,Y.,Zhang,X.et al.Functional tissue-engineered bone-like graft made of...
PubMed ID: 33574428, Karami S,Doroodmand MM,Taherianfar M,Mutabi-Alavi A,Nagshgar N.Mechanism behind ...
PubMed ID: 33574428, Karami S,Doroodmand MM,Taherianfar M,Mutabi-Alavi A,Nagshgar N.Mechanism behind ...
PubMed ID: 33564275, Fan J,He M,Wang CJ,Zhang M. Gadolinium Chloride Inhibits the Production of Liver...
PubMed ID: 33564275, Fan J,He M,Wang CJ,Zhang M. Gadolinium Chloride Inhibits the Production of Liver...

*More publications can be found for each product on its corresponding product page