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Facts about Tubulin alpha-1B chain.
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Human | |
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Gene Name: | TUBA1B |
Uniprot: | P68363 |
Entrez: | 10376 |
Belongs to: |
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tubulin family |
alpha tubulin; Alpha-tubulin ubiquitous; K-ALPHA-1; tubulin alpha-1B chain; Tubulin alpha-ubiquitous chain; Tubulin K-alpha-1; tubulin, alpha 1b; tubulin, alpha, ubiquitous
Mass (kDA):
50.152 kDA
Human | |
---|---|
Location: | 12q13.12 |
Sequence: | 12; NC_000012.12 (49127782..49131395, complement) |
Cytoplasm, cytoskeleton.
You might be a biomedical researcher wondering about the TUBA1B marker. This article explains how the TUBA1B marker and Anti alpha Tubulin antibodies work, as well ELISA Kits. We'll also review some other useful resources that might be of use to you. These resources will help you decide which products are most beneficial to your research.
The TUBA1B gene signature is a useful tool to detect inactive or dysfunctional immune cells. Its signature includes genes such as IL33, KLRC2, OLFM1, PDPN, SDC1, TNFSF9, VLDLR, and TNFSF9. Similarly, this marker can detect the expression of IL10RA, CTLA2A, and CCR2 to identify cancer cells and inflammatory tissues.
Boster Bio provides many advantages with its Anti-alpha Tubulin Antibody. It reacts to human, mouse, and rats Alpha-tubulin. This antibody can also be used in Western blot experiments. Its ability to bind antigens makes it a good choice in Western Blot experiments. You can also use it for Immunofluorescence.
The anti-alpha Tubulin antibody from BoSTER Bio can be used in various methods, including immunohistochemistry. The antibody has been tested for its specificity in IHC (inhibits the binding of antigens) and Western blot analysis (WB). The antibody comes in 100 ug/vial. It is compatible with whole cell lysates including hematology samples. It can be stored at 4degC for one month. The antibody is made from rabbits that have been immunized with a synthetic progesterone containing 408-439 amino acid. Boster has performed extensive validation of antigens to assure they are highly precise.
Boster Bio has developed an anti-alpha tubulin antibody that recognizes the UTP protein. This protein is an important component of the microtubules. Boster Bio offers an anti-alphatubulin antibody that is useful in immunocytochemistry experiments of neurons, cells from the glial and other tissues. It is also highly sensitive in immunofluorescence research.
Cultures of Abce1-treated mouse oocytes were performed for 0, 2,, 4.5, 8, 9, 9.5, and 14 hours. Abce1 was found in germinal nuclei and co-localized to a-tubulin. It is also useful in imaging the distribution of Abce1 during mouse oocyte development. The Abce1RNAi group showed the same pattern as that of the control group.
ELISA kits that detect the TUBA1B protein are available to detect it in crude preparations. They contain pre-coated anti-plates, detection antibodies and buffers. The Instant ELISA Kit provides a sample diluent, detection antibodies, and streptavidin HRP. The strip wells contain a standard curve.
The ELISA kit should have a stable performance. The expiration date should not exceed 5%. The kit must also be able to perform in a standard lab environment and operating procedure. The entire assay should be performed by the same person. These are the conditions for ELISA kits containing the TUBA1B indicator:
First, a microtiter plates has been pre-coated in an antibody specific for the index. The wells can then be enriched with biotin conjugated reagents or samples. The HRP enzymatic reactions are then performed by adding TMB substrate. The process ends with the measurement of the colour change from yellow to blue.
The ELISA kits designed for the TUBA1B antibody will add the correct amount to the plate. The primary antibody is the detection antibody, while the secondary antibody is the capture antibody. Indirect detection methods need a biotin/streptavidin compound or labeled second antibody. The most common method is sandwich ELISA. It involves two types if antigens. One is a biotin/streptavidin-based complex that captures a target antigen and one is a pre-coated antibody.
ELISA kits for TUBA1B include sandwich-based ELISAs and matched-pair ELISAs. The sandwich ELISA is known for its high specificity and sensitivity. The Sandwich ELISA Kit provides another method for measuring TUBA1B proteins. The sandwich ELISA can be used to detect TUBA1B protein even in complex samples.
CCN1 is one of many biomarkers that can be used to detect breast cancer early. It is found in liquid biopsy panels. The sequencing of blood tests results can help determine the best time to do mammography. Currently, screening programs follow a set standard for determining the best time to perform mammography. Flexible biomarker-driven ELISAs can take into account patient variability to improve accuracy and reduce screening intervals.
PMID: 6646120 by Cowan N.J., et al. Expression of human alpha-tubulin genes: interspecies conservation of 3' untranslated regions.
PMID: 8619814 by Baumann M.H., et al. C-terminal fragments of alpha- and beta-tubulin form amyloid fibrils in vitro and associate with amyloid deposits of familial cerebral amyloid angiopathy, British type.
*More publications can be found for each product on its corresponding product page