Tubby protein homolog Antibodies

AND TUB ELISA kits, Tubby protein homolog Proteins

Many biological assays use antibodies to detect Tubby protein homolog, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Tubby protein homolog in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Tubby protein homolog antibodies...

We validate the specificity of these antibodies to Tubby protein homolog by testing them on tissues known to express TUB positively and negatively. Browse below to find the TUB antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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TUB Infographic by Boster Bio

All TUB Products

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Product

Figures

Specificity

Applications

Price

Anti-TUB 1 Antibody Picoband®

4 Q&As

Human

Flow Cytometry, WB

$370
Cat # A02917-1
100 μg/vial

TUB (NM_177972) Human Recombinant Protein

$1062
Cat # PROTP50607
20 µg

Anti-TUB1 Rabbit Monoclonal Antibody

Human, Mouse, Rat

IHC, WB

$370
Cat # M02917
100 μl/vial

TUB (NM_177972) Human Over-expression Lysate

Human

$960
Cat # LS007275
100 µg

TUB Overview

Facts about Tubby protein homolog.

TUB 3D structure. Source: alphafold

Tubby protein homolog (TUB)

Functions in signal transduction from heterotrimeric G protein-coupled receptors. Binds to membranes containing phosphatidylinositol 4,5-bisphosphate.

Can bind DNA (in vitro). May contribute to the regulation of transcription in the nucleus.

Gene Information

Human
Gene Name:	TUB
Uniprot:	P50607
Entrez:	7275

Family

Belongs to:

TUB family

Alternative Names

RD5; RDOB; tubby (mouse) homolog; tubby homolog (mouse); Tubby Homolog; tubby homologue; tubby protein homolog; Tubby

Molecular Weight

Mass (kDA):
55.651 kDA

Genomic Context


Human

Location:	11p15.4
Sequence:	11; NC_000011.10 (8019180..8106243)

Subcellular Localizations

Cytoplasm. Nucleus. Secreted. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Binds phospholipid and is anchored to the plasma membrane through binding phosphatidylinositol 4,5-bisphosphate. Is released upon activation of phospholipase C. Translocates from the plasma membrane to the nucleus upon activation of guanine nucleotide-binding protein G(q) subunit alpha. Does not have a cleavable signal peptide and is secreted by a non-conventional pathway (By similarity).

Diseases

Obesity
Submersion
Pneumonia
Malignant Neoplasms
Extrinsic Allergic Alveolitis
Pseudomonas Infections
Retinal Degeneration
Pain
Infective Disorder
Neoplasms
Mycobacterium Avium-intracellulare Infection
Stomach Neoplasms
Lung Diseases

Malignant Neoplasm Of Stomach
Carcinoma
Neoplasm Metastasis
Diabetes Mellitus
Granuloma
Folliculitis
Cerebrovascular Accident

Pathways

Hypersensitivity
Swimming
Transport
Localization
Pathogenesis
Translation
Reverse Transcription
Cell Death
Secretion
Fermentation
Feeding Behavior
Phagocytosis
Locomotion

Cognition
Cell Proliferation
Cell Cycle
Nucleoside Transport
Oviposition
Phototransduction
Germination

PTMs

Phosphorylation
Cleavage
Demethylation
Reduction
Glycosylation

Deiodination
Dephosphorylation
Oxidation
Methylation
Ribosylation

Research Areas

Cell Biology
Cell Cycle and Replication
Cellular Markers
Chromatin Research
Neuroscience

Transcription Factors and Regulators

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TUB

References

PMID: 8612280 by Kleyn P.W., et al. Identification and characterization of the mouse obesity gene tubby: a member of a novel gene family.

PMID: 9096357 by North M.A., et al. Molecular characterization of TUB, TULP1, and TULP2, members of the novel tubby gene family and their possible relation to ocular diseases.