Ttll7 Antibodies

AND Ttll7 ELISA kits, Ttll7 Proteins

Many biological assays use antibodies to detect Ttll7, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Ttll7 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Ttll7 antibodies...

We validate the specificity of these antibodies to Ttll7 by testing them on tissues known to express Ttll7 positively and negatively. Browse below to find the Ttll7 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Ttll7 Infographic by Boster Bio

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TTLL7 (NM_024686) Human Over-expression Lysate

Human

$960
Cat # LS079739
100 µg

Ttll7 Overview

Facts about Tubulin polyglutamylase TTLL7.

Tubulin polyglutamylase TTLL7 (Ttll7)

Polyglutamylase which preferentially modifies beta- tubulin (PubMed:16901895, PubMed:17499049, PubMed:19152315). Mediates both ATP-dependent initiation and elongation of polyglutamylation of microtubules (PubMed:16901895, PubMed:19152315).

Required for neurite growth; responsible for the strong increase in tubulin polyglutamylation during postnatal neuronal maturation (PubMed:16901895). .

Gene Information

Mouse
Gene Name:	Ttll7
Uniprot:	A4Q9F0
Entrez:	70892

Family

Belongs to:

tubulin--tyrosine ligase family

Alternative Names

FLJ23033; FLJ36855; RP5-836J3.2; tubulin polyglutamylase TTLL7; tubulin tyrosine ligase-like family, member 7; tubulin--tyrosine ligase-like protein 7

Molecular Weight

Mass (kDA):
105.501 kDA

Genomic Context


Mouse

Location:	3\|3 H2
Sequence:	3;

Tissue Specificity

Widely expressed with highest levels in brain, testis and trachea. In brain, highly expressed in hippocampus, thalamus, olfactory bulb and cerebellum.

Diseases

Metabolic Diseases
Obesity
Nervousness

Pathways

Nucleosome Assembly

PTMs

Glutamylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Ttll7

References

PMID: 17499049 by van Dijk J., et al. A targeted multienzyme mechanism for selective microtubule polyglutamylation.

PMID: 16901895 by Ikegami K., et al. TTLL7 is a mammalian beta-tubulin polyglutamylase required for growth of MAP2-positive neurites.