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- Table of Contents
Facts about Tubulin--tyrosine ligase-like protein 12.
Human | |
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Gene Name: | TTLL12 |
Uniprot: | Q14166 |
Entrez: | 23170 |
Belongs to: |
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tubulin--tyrosine ligase family |
dJ526I14.2; KIAA0153FLJ41795; tubulin tyrosine ligase-like family, member 12; tubulin--tyrosine ligase-like protein 12
Mass (kDA):
74.404 kDA
Human | |
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Location: | 22q13.2 |
Sequence: | 22; NC_000022.11 (43166622..43187134, complement) |
Cytoplasm. Midbody. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Nucleus. Predominantly localizes in the cytoplasm (PubMed:28011935). Partially colocalizes with vimentin in prostate cancer cells (PubMed:20162578).
PMID: 20162578 by Wasylyk C., et al. Tubulin tyrosine ligase like 12 links to prostate cancer through tubulin posttranslational modification and chromosome ploidy.
PMID: 23251473 by Brants J., et al. Tubulin tyrosine ligase like 12, a TTLL family member with SET- and TTL-like domains and roles in histone and tubulin modifications and mitosis.