Ttll11 Antibodies

AND Ttll11 ELISA kits, Ttll11 Proteins

Many biological assays use antibodies to detect Ttll11, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Ttll11 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Ttll11 antibodies...

We validate the specificity of these antibodies to Ttll11 by testing them on tissues known to express Ttll11 positively and negatively. Browse below to find the Ttll11 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Ttll11 Infographic by Boster Bio

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TTLL11 (NM_194252) Human Over-expression Lysate

Human

$960
Cat # LS158135
100 µg

Ttll11 Overview

Facts about Tubulin polyglutamylase TTLL11.

Tubulin polyglutamylase TTLL11 (Ttll11)

Polyglutamase that preferentially modifies alpha- tubulin (PubMed:17499049). Involved from the side-chain elongation step of the polyglutamylation response as opposed to at the initiation step.

Needed for CCSAP localization to both spindle and cilia microtubules (PubMed:17499049). Generates long side- chains (PubMed:20530212).

Gene Information

Mouse
Gene Name:	Ttll11
Uniprot:	A4Q9F4
Entrez:	74410

Family

Belongs to:

tubulin--tyrosine ligase family

Alternative Names

bA244O19.1; C9orf20; RP11-429D3.1; TTLL11 tubulin tyrosine ligase-like family, member 11

Molecular Weight

Mass (kDA):
82.361 kDA

Genomic Context


Mouse

Location:	2 B\|2 23.9 cM
Sequence:	2;

Tissue Specificity

Widely expressed with highest levels in brain, kidney, liver, lung, muscle and testis.

Diseases

Mental Disorders
Autistic Disorder
Schizophrenia

Pathways

Pathogenesis

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Ttll11

References

PMID: 17499049 by van Dijk J., et al. A targeted multienzyme mechanism for selective microtubule polyglutamylation.

PMID: 20530212 by Lacroix B., et al. Tubulin polyglutamylation stimulates spastin-mediated microtubule severing.