TTF1 Antibodies

AND TTF1 ELISA kits, TTF1 Proteins

Many biological assays use antibodies to detect TTF1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TTF1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TTF1 antibodies...

We validate the specificity of these antibodies to TTF1 by testing them on tissues known to express TTF1 positively and negatively. Browse below to find the TTF1 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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TTF1 Infographic by Boster Bio

All TTF1 Products

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Product

Figures

Specificity

Applications

Price

Anti-TTF1 Antibody

Human, Mouse, Rat

$405
Cat # A01477
100ul

Anti-TTF-I TTF1 Antibody

Human

ELISA, IHC

$380
Cat # A01477-1
100ul

Transcription termination factor 1 (TTF1) (NM_007344) Human Over-expression Lysate

Human

$960
Cat # LS007270
100 µg

TTF1 Overview

Facts about Transcription termination factor 1.

TTF1 3D structure. Source: alphafold

Transcription termination factor 1 (TTF1)

Multifunctional nucleolar protein that terminates ribosomal gene transcription, mediates replication fork arrest and modulates RNA polymerase I transcription on chromatin. Plays a dual role in rDNA regulation, being involved in both activation and silencing of rDNA transcription.

Interaction with BAZ2A/TIP5 recovers DNA-binding activity. .

Gene Information

Human
Gene Name:	TTF1
Uniprot:	Q15361
Entrez:	7270

Family

Belongs to:

No superfamily

Alternative Names

RNA polymerase I termination factor; transcription termination factor 1; Transcription termination factor I; transcription termination factor, RNA polymerase I; TTF-1; TTF-I

Molecular Weight

Mass (kDA):
103.051 kDA

Genomic Context


Human

Location:	9q34.13
Sequence:	9; NC_000009.12 (132375548..132406851, complement)

Subcellular Localizations

Nucleus. Nucleus, nucleolus.

Diseases

Neoplasms
Carcinoma
Lung Neoplasms
Adenocarcinoma
Malignant Neoplasms
Malignant Neoplasm Of Lung
Neoplasm Metastasis
Malignant Squamous Cell Neoplasm
Non-small Cell Lung Carcinoma
Thyroid Neoplasm
Adenocarcinoma Of Lung (disorder)
Malignant Paraganglionic Neoplasm
Malignant Neoplasm Of Thyroid

Hypothyroidism
Small Cell Carcinoma Of Lung
Lung Diseases
Carcinoma, Neuroendocrine
Carcinoid Tumor
Carcinoma, Large Cell
Mammary Neoplasms

Pathways

Lung Development
Cell Differentiation
Localization
Cell Proliferation
Chromatin Remodeling
Lung Morphogenesis
Methylation
Cell Growth
Pathogenesis
Cell Death
Secretion
Cell Adhesion
Surfactant Homeostasis

Gland Development
Dna Methylation
Dna Replication
Dedifferentiation
Gene Silencing
Cell Cycle
Angiogenesis

PTMs

Phosphorylation
Methylation
Demethylation

Deiodination
Acetylation
Ubiquitination

Iodination

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TTF1

References

PMID: 7597036 by Evers R., et al. Molecular evolution of mammalian ribosomal gene terminator sequences and the transcription termination factor TTF-1.