Ttc21b Antibodies

AND Ttc21b ELISA kits, Ttc21b Proteins

Many biological assays use antibodies to detect Ttc21b, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Ttc21b in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Ttc21b antibodies...

We validate the specificity of these antibodies to Ttc21b by testing them on tissues known to express Ttc21b positively and negatively. Browse below to find the Ttc21b antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Ttc21b Infographic by Boster Bio

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TTC21B (NM_024753) Human Over-expression Lysate

Human

$628
Cat # LS079809
100 µg

Ttc21b Overview

Facts about Tetratricopeptide repeat protein 21B.

Tetratricopeptide repeat protein 21B (Ttc21b)

Component of the IFT complex A (IFT-A), a complex required for retrograde ciliary transport. Negatively modulates the SHH signal transduction.

Gene Information

Mouse
Gene Name:	Ttc21b
Uniprot:	Q0HA38
Entrez:	73668

Family

Belongs to:

TTC21 family

Alternative Names

ATD4; JBTS11; KIAA1992; putative protein product of Nbla10696; tetratricopeptide repeat domain 21B; tetratricopeptide repeat protein 21B; THM1; TPR repeat protein 21B

Molecular Weight

Mass (kDA):
150.795 kDA

Genomic Context


Mouse

Location:	2\|2 C1.3
Sequence:	2;

Diseases

Retinal Degeneration
Jeune Thoracic Dystrophy
Bardet-biedl Syndrome
Nephronophthisis
Kidney Diseases
Renal Dysplasia And Retinal Aplasia (disorder)
Familial Aplasia Of The Vermis
Nystagmus
Dysostoses
Curry-hall Syndrome
Meckel-gruber Syndrome
Complete Hearing Loss

Glioblastoma
Chronic Eosinophilic Leukemia
Cystic Kidney Diseases
Dystrophy
Short Rib-polydactyly Syndrome, Majewski Type
Usher Syndrome
Ciliary Motility Disorders

Pathways

Transport
Intraflagellar Transport
Brain Development
Forebrain Development

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Ttc21b

References

PMID: 18327258 by Tran P.V., et al. THM1 negatively modulates mouse sonic hedgehog signal transduction and affects retrograde intraflagellar transport in cilia.

PMID: 25860617 by Xu Y., et al. Characterization of tetratricopeptide repeat-containing proteins critical for cilia formation and function.