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- Table of Contents
Facts about Testis-specific serine/threonine-protein kinase 2.
Involved in the late stages of spermatogenesis, during the reconstruction of the cytoplasm. During spermatogenesis, required for the transformation of a ring-shaped structure around the base of the flagellum originating from the chromatoid body.
Mouse | |
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Gene Name: | Tssk2 |
Uniprot: | O54863 |
Entrez: | 22115 |
Belongs to: |
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protein kinase superfamily |
DGSG; DiGeorge syndrome protein G; EC 2.7.11; FLJ38613; serine/threonine kinase 22B (spermiogenesis associated); Serine/threonine-protein kinase 22B; spermiogenesis associated 2; SPOGA2EC 2.7.11.1; STK22BDGS-G; testis specific serine threonine kinase 2; Testis-specific kinase 2; testis-specific serine kinase 2; testis-specific serine/threonine-protein kinase 2; TSK-2; TSSK-2
Mass (kDA):
41.022 kDA
Mouse | |
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Location: | 16 A3|16 11.09 cM |
Sequence: | 16; |
Testis-specific. Expressed only in the spermatids postmeiotically at the final stages of cytodifferentiation in the seminiferous tubules (at protein level). Not detected in released sperms in the lumen of the seminiferous tubules. Also present in the epididymal sperm (at protein level).
PMID: 9412477 by Kueng P., et al. A novel family of serine/threonine kinases participating in spermiogenesis.
PMID: 9651519 by Nayak S., et al. Immunohistochemical analysis of the expression of two serine- threonine kinases in the maturing mouse testis.