This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
Facts about Teashirt homolog 3.
Associates with chromatin in a region surrounding the CASP4 transcriptional start site(s) (PubMed:19343227). Regulates the development of neurons involved in both respiratory rhythm and airflow management.
Human | |
---|---|
Gene Name: | TSHZ3 |
Uniprot: | Q63HK5 |
Entrez: | 57616 |
Belongs to: |
---|
teashirt C2H2-type zinc-finger protein family |
FLJ54422; KIAA1474; teashirt 3; teashirt zinc finger homeobox 3; zinc finger protein 537; ZNF537
Mass (kDA):
118.566 kDA
Human | |
---|---|
Location: | 19q12 |
Sequence: | 19; NC_000019.10 (31149876..31349436, complement) |
Expressed in brain; strongly reduced in post- mortem elderly subjects with Alzheimer disease (PubMed:18776146, PubMed:19343227). Expressed in the fetal neocortex (PubMed:27668656).
Nucleus. Cell projection, growth cone. Colocalizes with APBB1 in axonal growth cone (By similarity). Colocalizes with APBB1 in the nucleus.
PMID: 18776146 by Caubit X., et al. Teashirt 3 is necessary for ureteral smooth muscle differentiation downstream of SHH and BMP4.
PMID: 19343227 by Kajiwara Y., et al. FE65 binds Teashirt, inhibiting expression of the primate-specific caspase-4.