TRPV4 Antibodies

AND TRPV4 ELISA kits, TRPV4 Proteins

Many biological assays use antibodies to detect TRPV4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TRPV4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TRPV4 antibodies...

We validate the specificity of these antibodies to TRPV4 by testing them on tissues known to express TRPV4 positively and negatively. Browse below to find the TRPV4 antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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TRPV4 Infographic by Boster Bio

All TRPV4 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-TRPV4 Antibody

Human

ELISA, IF, IHC-P, WB

$449
Cat # A00565
0.1 mg

Anti-TRPV4 Antibody

Human, Mouse, Rat

ELISA, WB

$380
Cat # A00565-1
100ul

Anti-TRPV4 Antibody Picoband®

Human, Mouse, Rat

ELISA, WB

$370
Cat # A00565-2
100 μg/vial

TRPV4 (NM_021625) Human Over-expression Lysate

Human

$960
Cat # LS059341
100 µg

Anti-TRPV4 Antibody Picoband®

Human, Mouse, Rat

ELISA, WB

$370
Cat # A00565-3
100 μg/vial

TRPV4 Overview

Facts about Transient receptor potential cation channel subfamily V member 4.

TRPV4 3D structure. Source: alphafold

Transient receptor potential cation channel subfamily V member 4 (TRPV4)

Non-selective calcium permeant cation channel involved in osmotic sensitivity and mechanosensitivity. Also activated by heat, low pH, citrate and phorbol esters (PubMed:16293632, PubMed:18826956, PubMed:18695040, PubMed:25256292, PubMed:20037586, PubMed:21964574).

Increase of intracellular Ca(2+) potentiates currents. Channel activity appears to be controlled by a calmodulin-dependent mechanism using a negative feedback mechanism (PubMed:12724311, PubMed:18826956).

Gene Information

Human
Gene Name:	TRPV4
Uniprot:	Q9HBA0
Entrez:	59341

Family

Belongs to:

transient receptor (TC 1.A.4) family

Alternative Names

CMT2Cosmosensitive transient receptor potential channel 4; HMSN2C; Osm-9-like TRP channel 4; OTRPC4SSQTL1; transient receptor potential cation channel subfamily V member 4; transient receptor potential cation channel, subfamily V, member 4; Transient receptor potential protein 12; TRP12OSM9-like transient receptor potential channel 4; TrpV4; Vanilloid receptor-like channel 2; Vanilloid receptor-like protein 2; vanilloid receptor-related osmotically activated channel; Vanilloid receptor-related osmotically-activated channel; VRL2; VRL-2; VR-OAC; VROACSPSMA

Molecular Weight

Mass (kDA):
98.281 kDA

Genomic Context


Human

Location:	12q24.11
Sequence:	12; NC_000012.12 (109783087..109833398, complement)

Tissue Specificity

Found in the synoviocytes from patients with (RA) and without (CTR) rheumatoid arthritis (at protein level).

Subcellular Localizations

Apical cell membrane; Multi-pass membrane protein. Cell junction, adherens junction. Cell projection, cilium. Assembly of the putative homotetramer occurs primarily in the endoplasmic reticulum.; [Isoform 1]: Cell membrane.; [Isoform 5]: Cell membrane.; [Isoform 2]: Endoplasmic reticulum.; [Isoform 4]: Endoplasmic reticulum.; [Isoform 6]: Endoplasmic reticulum.