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- Table of Contents
Facts about Transient receptor potential cation channel subfamily M member 3.
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Human | |
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Gene Name: | TRPM3 |
Uniprot: | Q9HCF6 |
Entrez: | 80036 |
Belongs to: |
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transient receptor (TC 1.A.4) family |
EC 2.3.1.31; EC 5.99.1.3; Long transient receptor potential channel 3; LTrpC3; LTrpC-3; LTRPC3KIAA1616MLSN2GON-2; melastatin 2; melastatin-2; transient receptor potential cation channel subfamily M member 3; transient receptor potential cation channel, subfamily M, member 3
Mass (kDA):
197.571 kDA
Human | |
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Location: | 9q21.12-q21.13 |
Sequence: | 9; NC_000009.12 (70529060..71446971, complement) |
Expressed primarily in the kidney and, at lower levels, in brain, testis, ovary, pancreas and spinal cord. Expression in the brain and kidney was determined at protein level. In the kidney, expressed predominantly in the collecting tubular epithelium in the medulla, medullary rays, and periglomerular regions; in the brain, highest levels are found in the cerebellum, choroid plexus, the locus coeruleus, the posterior thalamus and the substantia nigra. Down-regulated in renal tumors compared to normal kidney.
Membrane; Multi-pass membrane protein.
PMID: 12672799 by Grimm C., et al. Molecular and functional characterization of the melastatin-related cation channel TRPM3.
PMID: 12672827 by Lee N., et al. Expression and characterization of human transient receptor potential melastatin 3 (hTRPM3).