TRIM2 Antibodies

AND TRIM2 ELISA kits, TRIM2 Proteins

Many biological assays use antibodies to detect TRIM2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TRIM2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TRIM2 antibodies...

We validate the specificity of these antibodies to TRIM2 by testing them on tissues known to express TRIM2 positively and negatively. Browse below to find the TRIM2 antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Previous: SEPTIN9 Next: MAN2B2

TRIM2 Infographic by Boster Bio

All TRIM2 Products

Product

Figures

Specificity

Applications

Price

Anti-RNF86 (TRIM2) Mouse Monoclonal Antibody [Clone ID: OTI4E5]

Human, Mouse, Rat

Flow Cytometry, WB

$523
Cat # M08957-1
100 µl

Anti-RNF86 (TRIM2) Mouse Monoclonal Antibody [Clone ID: OTI3B5]

Human, Mouse, Rat

IF, WB

$523
Cat # M08957-2
100 µl

Anti-RNF86 (TRIM2) Mouse Monoclonal Antibody [Clone ID: OTI2B10]

Human, Mouse, Rat

Flow Cytometry, WB

$523
Cat # M08957
100 µl

RNF86 (TRIM2) (NM_015271) Human Over-expression Lysate

Human

$628
Cat # LS023321
100 µg

Anti-TRIM2 Antibody Picoband™

Human, Mouse, Rat

ELISA, IHC, WB

$370
Cat # A08957
100 µg/vial

TRIM2 Overview

Facts about Tripartite motif-containing protein 2.

TRIM2 3D structure. Source: alphafold

Tripartite motif-containing protein 2 (TRIM2)

UBE2D1-dependent E3 ubiquitin-protein ligase that mediates the ubiquitination of NEFL and of phosphorylated BCL2L11. Plays a neuroprotective function.

May play a role in neuronal rapid ischemic tolerance. .

Gene Information

Human
Gene Name:	TRIM2
Uniprot:	Q9C040
Entrez:	23321

Family

Belongs to:

TRIM/RBCC family

Alternative Names

KIAA0517tripartite motif protein 2; RING finger protein 86; RNF86tripartite motif protein TRIM2; tripartite motif containing 2; tripartite motif-containing 2; tripartite motif-containing protein 2

Molecular Weight

Mass (kDA):
81.53 kDA

Genomic Context


Human

Location:	4q31.3
Sequence:	4; NC_000004.12 (153152163..153339317)

Subcellular Localizations

Cytoplasm.

Diseases

Carcinoma
Carcinogenesis
Malignant Neoplasms
Neoplasms
Malignant Squamous Cell Neoplasm
Intracranial Arteriovenous Malformation
Neoplasm Metastasis
Adenoma
Brain Ischemia
Intraepithelial Neoplasia
Neurodegenerative Disorders
Uterine Cervical Neoplasm
Ataxia

Bone Neoplasms
Arteriovenous Malformation
Mouth Neoplasms
Tumor Angiogenesis
Nervousness
Cervical Intraepithelial Neoplasia
Follicular Adenoma

Interacting Proteins

CDK20
CIB3
LRRC8E
TRIM3
UBAC1

Pathways

Pathogenesis
Neuroprotection
Translation
Cell Death
Brain Development
Angiogenesis

Rna Interference

PTMs

Ubiquitination

Phosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TRIM2

References

PMID: 11331580 by Reymond A., et al. The tripartite motif family identifies cell compartments.

PMID: 21478148 by Thompson S., et al. Identification of a novel Bcl-2-interacting mediator of cell death (Bim) E3 ligase, tripartite motif-containing protein 2 (TRIM2), and its role in rapid ischemic tolerance-induced neuroprotection.