TRAF1 Antibodies

AND TRAF1 ELISA kits, TRAF1 Proteins

Many biological assays use antibodies to detect TRAF1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TRAF1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TRAF1 antibodies...

We validate the specificity of these antibodies to TRAF1 by testing them on tissues known to express TRAF1 positively and negatively. Browse below to find the TRAF1 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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TRAF1 Infographic by Boster Bio

All TRAF1 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-TRAF1 Antibody Picoband®

6 Q&As

Human, Mouse

$370
Cat # PA2006
100 μg/vial

Anti-TRAF1 Antibody Picoband®

Human

ELISA, Flow Cytometry, WB

$370
Cat # A01365
100 μg/vial

Human TRAF-1 Recombinant Protein

SDS-PAGE

$243
Cat # PROTQ13077
Starting from 20ug

TRAF1 (NM_005658) Human Over-expression Lysate

Human

$628
Cat # LS007185
100 µg

TRAF1 Overview

Facts about TNF receptor-associated factor 1.

TRAF1 3D structure. Source: alphafold

TNF receptor-associated factor 1 (TRAF1)

Adapter molecule that regulates the activation of NF- kappa-B and JNK. Plays a role in the regulation of cell survival and apoptosis.

The heterotrimer formed by TRAF1 and TRAF2 is part of a E3 ubiquitin-protein ligase complex that promotes ubiquitination of target proteins, such as MAP3K14. The TRAF1/TRAF2 complex recruits the antiapoptotic E3 protein- ubiquitin ligases BIRC2 and BIRC3 to TNFRSF1B/TNFR2.

Gene Information

Human
Gene Name:	TRAF1
Uniprot:	Q13077
Entrez:	7185

Family

Belongs to:

No superfamily

Alternative Names

EBI6; EBI6MGC:10353; Epstein-Bar virus-induced protein 6; Epstein-Barr virus-induced protein 6; TNF receptor-associated factor 1; TRAF1; TRAF-1

Molecular Weight

Mass (kDA):
46.164 kDA

Genomic Context


Human

Location:	9q33.2
Sequence:	9; NC_000009.12 (120902393..120929173, complement)

Diseases

Rheumatoid Arthritis
Arthritis
Lymphoma
Malignant Neoplasms
Neoplasms
Inflammation
Hodgkin Disease
Autoimmune Reaction
Autoimmune Diseases
Tumor Angiogenesis
Malignant Paraganglionic Neoplasm
Cell Invasion
Carcinoma

Diffuse Large B-cell Lymphoma
B-cell Lymphomas
Epstein-barr Virus Infections
Leukemia
Tissue Adhesions
Lupus Erythematosus, Systemic
Ki-1+ Anaplastic Large Cell Lymphoma

Pathways

Cell Death
Pathogenesis
Angiogenesis
Cell Proliferation
Localization
Cell Activation
Immune Response
Secretion
Programmed Cell Death
Cell Growth
Cell Adhesion
B Cell Activation
Reverse Transcription

Cell Cycle
Induction Of Apoptosis
T Cell Activation
Inflammatory Response
Translation
Rna Interference
Cell Migration

PTMs

Phosphorylation
Cleavage
Ubiquitination
Citrullination

Reduction
Acetylation
Methylation
Acylation

Myristoylation

Research Areas

Apoptosis
Cancer
Cytokine Research

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TRAF1

References

PMID: 7859281 by Mosialos G., et al. The Epstein-Barr virus transforming protein LMP1 engages signaling proteins for the tumor necrosis factor receptor family.

PMID: 8069916 by Rothe M., et al. A novel family of putative signal transducers associated with the cytoplasmic domain of the 75 kDa tumor necrosis factor receptor.