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Metalloprotease TIKI1 Antibodies

AND TRABD2A ELISA kits, Metalloprotease TIKI1 Proteins

Many biological assays use antibodies to detect Metalloprotease TIKI1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Metalloprotease TIKI1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Metalloprotease TIKI1 antibodies...

We validate the specificity of these antibodies to Metalloprotease TIKI1 by testing them on tissues known to express TRABD2A positively and negatively. Browse below to find the TRABD2A antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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TRABD2A Infographic by Boster Bio

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C2orf89 (TRABD2A) (NM_001080824) Human Over-expression Lysate

Human

$960
Cat # LS129293
100 µg

TRABD2A Overview

Facts about Metalloprotease TIKI1.

TRABD2A 3D structure

TRABD2A 3D structure. Source: alphafold

Metalloprotease TIKI1 (TRABD2A)

Metalloprotease that functions as a negative regulator of the Wnt signaling pathway by mediating the cleavage of the 8 N- terminal residues of a subset of Wnt proteins. After cleavage, Wnt proteins become oxidized and form big disulfide-bond oligomers, leading to their inactivation.

Able to cleave WNT3A, WNT5, but not WNT11. Required for head formation.

Gene Information

Human
Gene Name:	TRABD2A
Uniprot:	Q86V40
Entrez:	129293

Gene Information

Family

Belongs to:

TIKI family

Family

Alternative Names

C2orf89; LOC129293; Tiki1; TRABD2A

Molecular Weight

Mass (kDA):
57.676 kDA

Molecular Weight

Genomic Context


Human

Location:	2p11.2
Sequence:	2; NC_000002.12 (84821650..84881975, complement)

Subcellular Localizations

Cell membrane; Single-pass type I membrane protein.

Subcellular Localization

PTMs

Glycoprotein

Bosterbio | ELISA Kits, Antibodies, Antibody Company

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TRABD2A

References

PMID: 22726442 by Zhang X., et al. Tiki1 is required for head formation via Wnt cleavage-oxidation and inactivation.