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- Table of Contents
Facts about Tropomyosin alpha-3 chain.
Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments.
Human | |
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Gene Name: | TPM3 |
Uniprot: | P06753 |
Entrez: | 7170 |
Belongs to: |
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tropomyosin family |
cytoskeletal tropomyosin TM30; FLJ41118; gamma-tropomyosin; heat-stable cytoskeletal protein 30 kDa; hscp30; hTM5; MGC14582; MGC3261; MGC72094; NEM1; OK/SW-cl.5; TM3; TM30; TM30nm; TM-5; TPMsk3; TRK; tropomyosin 3; tropomyosin alpha-3 chain; tropomyosin gamma; tropomyosin-3; tropomyosin-5
Mass (kDA):
32.95 kDA
Human | |
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Location: | 1q21.3 |
Sequence: | 1; NC_000001.11 (154155304..154192100, complement) |
Cytoplasm, cytoskeleton.
PMID: 3018581 by Reinach F.C., et al. Tissue-specific expression of the human tropomyosin gene involved in the generation of the trk oncogene.
PMID: 3024106 by McLeod A.R., et al. The mRNA and RNA-copy pseudogenes encoding TM30nm, a human cytoskeletal tropomyosin.