Tensin-2 Antibodies

AND TNS2 ELISA kits, Tensin-2 Proteins

Many biological assays use antibodies to detect Tensin-2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Tensin-2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Tensin-2 antibodies...

We validate the specificity of these antibodies to Tensin-2 by testing them on tissues known to express TNS2 positively and negatively. Browse below to find the TNS2 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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TNS2 Infographic by Boster Bio

All TNS2 Products

Product

Figures

Specificity

Applications

Price

Anti-Phospho-Tensin-2 (Y483) Antibody

3 Q&As

Human, Mouse

$399
Cat # P07021
100μl

Anti-Phospho Tensin-2 (Tyr483) Antibody

1 Q&As

Human, Mouse

ELISA, WB

$335
Cat # P30917
100ul

Anti-Tensin-2 TNS2 Antibody

Human, Mouse

ELISA, WB

$380
Cat # A07021
100ul

TENC1 (TNS2) (NM_015319) Human Over-expression Lysate

Human

$960
Cat # LS023371
100 µg

TNS2 Overview

Facts about Tensin-2.

TNS2 3D structure. Source: alphafold

Tensin-2 (TNS2)

Regulates cell motility and proliferation. May have phosphatase activity.

Reduces AKT1 phosphorylation. Lowers AKT1 kinase activity and interferes with AKT1 signaling.

Gene Information

Human
Gene Name:	TNS2
Uniprot:	Q63HR2
Entrez:	23371

Family

Belongs to:

PTEN phosphatase protein family

Alternative Names

Tensin-2

Molecular Weight

Mass (kDA):
152.58 kDA

Genomic Context


Human

Location:	12q13.13
Sequence:	12; NC_000012.12 (53046980..53064379)

Tissue Specificity

Detected in heart, kidney, brain, thymus, spleen, liver, placenta, lung, skeletal muscle and small intestine.

Subcellular Localizations

Cell junction, focal adhesion. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Detected at the end of actin stress fibers. Detected in cytoplasmic punctate bodies (PubMed:22019427).

Interacting Proteins

C11orf87
ERBB2
ERBB3
KIT
KPRP

KRTAP10-5
KRTAP10-7
KRTAP10-8
KRTAP12-2
MET

NUBP2
OTX1
PKP1
REEP6
REL

RYDEN
TEKT5
ZNF417
ZNF497
ZNF587

PTMs

Methylation

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TNS2

References

PMID: 12470648 by Hafizi S., et al. Interaction of Axl receptor tyrosine kinase with C1-TEN, a novel C1 domain-containing protein with homology to tensin.

PMID: 11792844 by Chen H., et al. Tensin1 and a previously undocumented family member, tensin2, positively regulate cell migration.