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- Table of Contents
Facts about Troponin T, cardiac muscle.
Human | |
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Gene Name: | TNNT2 |
Uniprot: | P45379 |
Entrez: | 7139 |
Belongs to: |
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troponin T family |
Cardiac Muscle Troponin T; Cardiomyopathy, Dilated 1D (Autosomal Dominant); Cardiomyopathy, Hypertrophic; CMD1D; CMH2; CMPD2; cTnT; LVNC6; RCM3; TNNT2; TnTC; troponin T type 2 (cardiac); Troponin T; troponin T, cardiac muscle; Troponin T2, Cardiac Type; Truncated Cardiac Troponin T
Mass (kDA):
35.924 kDA
Human | |
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Location: | 1q32.1 |
Sequence: | 1; NC_000001.11 (201359014..201377828, complement) |
Heart. The fetal heart shows a greater expression in the atrium than in the ventricle, while the adult heart shows a greater expression in the ventricle than in the atrium. Isoform 6 predominates in normal adult heart. Isoforms 1, 7 and 8 are expressed in fetal heart. Isoform 7 is also expressed in failing adult heart.
PMID: 8344420 by Mesnard L., et al. Molecular cloning and developmental expression of human cardiac troponin T.
PMID: 8088824 by Townsend P.J., et al. Human cardiac troponin T: identification of fetal isoforms and assignment of the TNNT2 locus to chromosome 1q.